Transmedics, Inc.

Doug Harriott

Scott W Newell

Waleed H Hassanein

Tamer I Khayal

Richard Bringham

John Sullivan

Stanley Kyi

Robert Havener

Robert Fishman

Mark Anderson

Ihab Abdel Fattah

Anas Abdelazim

Paul Murray

Michael Van Driel

Matthew De Remer

Ron Taylor

Tom Bishop

Tamer Khayal

Waleed Hassanein

Scott Newell

Thomas H Bishop

Ronald Taylor

Methods and systems of maintaining, evaluating, and providing therapy to a lung ex vivo. The methods and systems involve positioning the lung in an ex vivo perfusion circuit; circulating a perfusion fluid through the lung, the fluid entering the lung through a pulmonary artery interface and leaving the lung through a left atrial interface; and ventilating the lung by flowing a ventilation gas through a tracheal interface. Maintaining the lung for extended periods involves causing the lung to rebreath a captive volume of air, and reaching an equilibrium state between the perfusion fluid and the ventilation gas. Evaluating the gas exchange capability of the lung involves deoxygenating the perfusion fluid and measuring a time taken to reoxygenate the perfusion fluid by ventilating the lung with an oxygenation gas.

Systems and methods for ex vivo lung care

Growing community of inventors

Melrose, MA, United States of America

Doug Harriott