Viropharma Incorporated

Dorothy C Young

Thomas R Bailey

Guy D Diana

Theodore John Nitz

William P Gorczyca

John Swestock

Tandy D Goldstein

Methods are provided for the treatment and prophylaxis of viral infection and disease associated with such infection.

Methods for treating viral infections

Methods for treating or preventing viral infections and associated diseases

A compound produced by the process comprising the step of reacting a starting compound of the formula:

Compounds, compositions and methods for treating influenza

Compounds of the formula: ##STR1## wherein R1 represents a lower alkyl (C1-C6) substituent which may be straight or branched; R2 represents an aryl substituent of the formula: ##STR2## and Q, V, W, X, Y and Z are as set forth in the accompanying specification, are useful in prophylaxis of influenza virus infection.

A compound of the formula: ##STR1## wherein R.sub.1 represents a lower alkyl (C.sub.1 --C.sub.6) substituent which may be straight or branched; R.sub.2 represents an aryl substituent of the formula: ##STR2## and Q, V, W, X, Y and Z are as set forth in the accompanying specification. These compounds are useful in prophylaxis and treatment of influenza virus infection.

Compounds compositions and methods for treating influenza

Substituted pyrazole dimers are useful in prophylaxis and treatment of influenza virus infections.

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Collegeville, PA, United States of America

Dorothy C Young