J.p.m.e.d. Ltd.

Farmo-nat Ltd.

Other

Doron I Friedman

Michael M Friedman

Orna Levin

Yochanan Forman

This invention provides topical pharmaceutical or cosmetic compositions, and uses thereof in treating a disease or condition of the hair follicle. The compositions of this invention are emulsions of an oil-in-polyol with a mean particle size of below one micron, and further comprising at least one oil, one polyol, and one stabilizer.

Hair follicle targeting compositions

The present invention provides a composition of low water solubility drug, dissolved or dispersed in a non crystalline or low crystalline form in an emulsion type composition of internal oily-solvent and external non-hydrous and water soluble solvent, whereas 1) emulsifying stabilizer comprises low fraction of the composition, and 2) emulsions of mean droplets size below one micron is obtained upon dilution with physiological fluids, and 3) facilitated dispersion of biologically active agents in body fluids is obtained, and more particularly to facilitating biological availability or improving clinical performance.

Non-aqueous compositions for oral delivery of insoluble bioactive agents

The present invention relates to a homogeneous solid matrix composition containing vegetable proteins, lecithin and at least one ingestible bioactive compound which is at least partially insoluble in an aqueous medium.

Homogenous granular solid matrix containing vegetable protein

The invention provides a cosmetic or pharmaceutical composition in the form of an oil-in-glycerin emulsion, with mean droplet size below one micron, comprising a continuous glycerin phase, at least one vegetable oil comprising an internal phase, at least one emulsifying stabilizer, and at least one bioactive compount comprising at least one hydrophobic, moiety within its structure, wherein the composition facilitates stratum-corneum penetration and dermal penetration of said bioactive compound.

Nano oil in glycerin emulsion

The invention provides a composition of matter comprising a stable oil-in-glycerin emulstion containing at least one oil, at least one emulsifier and glycerin.

Stable oil-in-glycerin emulsion

An anti-fungal composition, including: (a) an extract of botanical materials, the botanical materials including material from Echinacea species, and Propolis, which is a material derived from the hives of bees; and (b) an essential oil. The compositions of the present invention have been shown to have unexpectedly prolonged anti-fungal activity, as well as having anti-bacterial and anti-inflammatory activities. Preferably, the essential oil includes at least one oil selected from the group consisting of tea-tree oil, thyme oil and lavander oil. Also preferably, the herbal extract includes a mixture of Calendula, poke root, Echinacea and Propolis extract.

Anti-fungal compositions with prolonged activity

A synergistic anti-bacterial composition, including: (a) an extract of botanical materials, the botanical materials including material from Plantago species, Hypericum species, Echinacea species and Propolis; and (b) oil of cinnamon.

Synergistic herbal extracts

An effervescent granule for the release and efficient dispersion of a herbal preparation in water. Also provided is a method of making the phytomedicated granule and a method of using the granule. The granule of the present invention is particularly efficient for the dispersion of a herbal preparation which includes an essential oil, although herbal preparations including an herbal extract can also be used.

Effervescent granules

A tablet for the local and slow release of herbal medication into the oral cavity of a subject. Also provided is a method of making the tablet and a method of using the tablet. The tablet includes a pharmaceutically effective amount of a herbal medication, a polymeric matrix material such as ethyl cellulose, a release enhancer such as PEG 4000 and a filler such as lactose. The tablet is characterized by long dissolution times of up to 120 minutes.

Growing community of inventors

Karme Yosef, Israel

Doron I Friedman