Other

United States of America, As Represented by the Secretary of Agriculture

Virginia Commonwealth University

Dorne R Yager

Robert F Diegelmann

I Kelman Cohen

J Vincent Edwards

Judson Vincent Edwards

Kelman I Cohen

Sequestrants and inhibitors of protease are applied to the wound site through the use of wound dressing based carrier systems to which they may be optionally ionically or covalently bound for the purpose of the initiation or enhancement of healing associated with chronic non-healing wounds.

Saccharide derivatives especially useful in wound dressings

Wound dressings with protease-lowering activity

The invention provides wound dressings and methods of their use, especially for the treatment of chronic, non-healing wounds. The wound dressings are composed of a support matrix, such as cotton cellulose, and an active agent associated with the support matrix. The active agent may be a protease inhibitor or a protease sequestrant, in particular an inhibitor or sequestrant of a neutrophil-derived cationic protease such as elastase.

Preparation of peroxide-oxidized, sulfonated, and phosphorylated cotton

Growing community of inventors

Chesterfield, VA, United States of America

Dorne R Yager