Genentech, Inc.

F. Hoffmann-La Roche Ag

Doris Kim

Anan Chuntharapai

Terence Wong

Cherie Louise Green

Omar Kabbarah

YounJeong Choi

The present application relates to anti-PD-L1 antibodies and their use to detect PD-L1 in a sample from a subject. In some embodiments, the subject has been treated with a therapeutic anti-PD-L1 antibody and an anti-PD-L1 described herein does not compete for binding to PD-L1 with the therapeutic anti-PD-L1 antibody. In some embodiments, the anti-PD-L1 antibody is linked to a N detectable moiety, such as a fluorophore and the anti-PD-L1 antibody is used to detect PD-L1 in a subject using flow cytometry.

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San Francisco, CA, United States of America

Doris Kim