Sri International

Mount Sinai School of Medicine

New York Medical College

Doris J Bucher

Amrit K Judd

Steven W Popple

Mohamed W Khan

Igor G Kharitonenkov

Peptides substantially corresponding to the 148-162 region of type A influenza M protein and additionally containing at least one amino acid in the 163-166 region are disclosed to have high activity as influenza transcription inhibitors and thus as antiviral agents against influenza virus and other RNA viruses. The modification of these peptides by incorporation into liposomes or by addition of long-chain alkylamino acids is also shown as in the use of all such materials in antiviral drug formulations.

M-protein peptides of influenza virus as antiviral agents

Macromolecular conjugates of a synthetic polypeptide having influenza virus antigenic properties are disclosed. These conjugates contain a polypeptide corresponding substantially to the 215-235 region of the matrix protein (M-protein) of influenza virus.

Conjugates of a synthetic peptide for diagnosis and prevention of

Synthetic polypeptides having influenza virus antigenic properties are disclosed. These polypeptides correspond substantially to the 215 to 235 region of the matrix protein of influenza virus. Salts, derivatives, and conjugates of these polypeptides are disclosed as well as methods for using these materials for diagnostic and medical/veterinary purposes.

Synthetic peptides for diagnosis and prevention of influenza virus

Synthetic polypeptides having influenza virus antigenic properties are disclosed. These polypeptides correspond substantially to particular regions in the matrix protein of influenza virus. Salts, derivatives, and conjugates of these polypeptides are disclosed as well as methods for using these materials for diagnostic and medical/veterinary purposes.

Growing community of inventors

New York, NY, United States of America

Doris J Bucher