United States of America, As Represented by the Secretary of Agriculture

Cold Spring Harbor Laboratory

Doreen Ware

John J Burke

Zhanguo Xin

Gloria B Burow

Yinping Jiao

Chad M Hayes

The present disclosure provides nucleic acids that confer a multi-seeded phenotype when expressed in plants and uses thereof.

Sorghum yield enhancement gene

Genetically altered sorghum plants expressing the multi-seeded #2 phenotype contain one of two genomic alterations in the Sb06g018040 gene which result in reduced activity of the encoded protein, a class II 13-lipoxygenase. This phenotype and genotype are referred to as msd2. These alterations result in increased number of seeds and seed weight, thus increasing the yield of the genetically altered plant. These alterations can be generated in the ortholog genes in maize (TS1), rice, barley, and other monocot plants, generating the MSD2 phenotype. The seeds of one particular MSD2has been deposited with ATCC and assigned Accession Number PTA-121634.

Mutant sorghum bicolor having enhanced seed yield

Growing community of inventors

Melville, NY, United States of America

Doreen Ware