Chonnam National University

Doo Sun Sim

Jong Oh Park

Jun Kyu Park

Suk Ho Park

Myung Ho Jeong

Dae Sung Park

So Youn Lee

Eun Jae Jang

Kyung Seob Lim

In-Ho Bae

Jae Won Shim

In Soo Kim

Se Mi Jeong

Kyung Rae Cha

Hyun Chol Choi

Suk Min Kim

A tacrolimus drug-eluting stent manufacturing method according to the present invention enables a tacrolimus drug to be strongly and stably bound onto a stent, while also not necessarily involving a separate step of introducing a surface-binding functional group for the binding of a drug onto a stent and a step of introducing, into the drug, a functional group capable of binding to the surface-binding functional group, and a tacrolimus drug-eluting stent manufactured by the manufacturing method has a greater total drug elution amount and has a more excellent delayed drug-elution property.

Non-polymeric tacrolimus drug-eluting stent and manufacturing method therefor

Provided is a drug-eluting coronary stent. In the drug-eluting coronary stent according to the present invention, electrospinning is used, thereby making it possible to precisely control a total content of an everolimus-based drug bound thereto and form a uniform layer in spite of not using a polymer causing late thrombosis, or the like.

Method of manufacturing polymer-free everolimus-eluting coronary stent fabricated by electrospinning technique

Growing community of inventors

Gwangju, South Korea

Doo Sun Sim