Bayer Pharmaceuticals Corporation

Bayer Healthcare LLC

Bayer Intellectual Property Gmbh

Bayer Schering Pharma Ag

Dongping Fan

Chengzhi Zhang

Jacques P Dumas

Gaetan H Ladouceur

Barton W Phillips

Wendy Lee

Qian Zhao

Benjamin Jones

Zhi Chen

Michael J Burke

Roger Astbury Smith

Jason A Duquette

Jianmei Fan

Holia Hatoum-Mokdad

Sharad Verma

Qingming Zhu

Scott Wilhelm

Georgiy Bondar

William Johnston Scott

Andreas Stolle

Yuanwei Chen

Julie A Dixon

Qingjie Liu

Philip Coish

Brent Chandler

Catherine R Brennan

Yingfu Li

Donald Bierer

Karl Miranda

Barry Hart

Mary Katherine Monahan

The invention relates to novel heterocycles of formula (I) processes for their preparation and their use for preparing medicaments for the treatment or prophylaxis of disorders, especially of hyperproliferative disorders. 

Pyrimidinothienoindazoles useful for the treatment of hyperproliferative disorders

This invention relates to novel compounds and processes for their preparation, methods of treating diseases, particularly hyperproliferative diseases such as cancer, comprising administering said compounds, and methods of making pharmaceutical compositions for the treatment or prevention of disorders, particularly hyperproliferative diseases such as cancer.

Heterocycles

This invention relates to novel benzofuran and benzothiophene derivatives of the general formula and their use for the treatment of hyper-proliferative disorders.

Benzofuran and benzothiophene derivatives useful in the treatment of hyper-proliferative disorders

This invention relates to a novel fused tricyclic heterocycle of the formula and its use for the treatment of hyper-proliferative disorders.

Fused tricyclic heterocycles useful for treating hyper-proliferative disorders

This invention relates to novel benzofuran and benzothiophene derivatives of the general table formula and their use for the treatment of hyper-proliferative disorders 

The present invention relates to a compound of Formula (I) and its use in treating lung and breast cancer. 

Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders

This invention relates to a novel fused tricyclic heterocycle of the formula (Ia, Ib) and its use for the treatment of hyper-proliferative disorders 

The invention relates to 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same and their use to treat or prevent diseases and conditions mediated by the phosphodiesterase enzyme 7(PDE7). Diseases and conditions mediated by PDE7include osteoporosis, osteopenia and asthma.

4-AMINO-5,6-SUBSTITUTED THIOPHENO [2,3-D] PYRIMIDINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME, AND THEIR USE IN THE TREATMENT OR PREVENTION OF PDE7B-MEDIATED DISEASES AND CONDITIONS

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North Haven, CT, United States of America

Dongping Fan