Samsung Electronics Co., Ltd.

Korea Research Institute of Bioscience and Biotechnology

Donghee Lee

Young Woo Park

Junho Kim

Jung Jae Yu

Ji Hyun Park

Jaesub Kim

Yangwoo Roh

Kiwon Jo

Yun Jung Park

Chan-Woong Park

Eun Jin Kim

Minkyeong Lee

Youkun Shin

A method of operating a storage controller which communicates with a host device and a non-volatile memory device is provided. The method includes: receiving a first command from the host device indicating a read operation of first status information of a first zone random write area (ZRWA) in a first zone region, wherein the first command complies with a zoned namespace (ZNS) standard; obtaining the first status information from a zone status table in the storage controller based on the first command, wherein the first status information indicates at least a portion of a first physical region of the non-volatile memory device corresponding to the first ZRWA in which first data are stored; and providing the first status information to the host device.

Storage controller providing status information of zone region, method of operating the same, and method of operating electronic device having the same

A recombinant expression vector, comprising extracellular soluble domain genes of DLK1 and IgG antibody Fc domain genes, is constructed, and DLK1-Fc fusion protein is expressed and purified at 293E cell. The invention confirmed the efficacy as a drug for inhibiting cancer metastasis by confirming markedly reduced migration of cancer cells by DLK1-Fc fusion protein and also computing pharmacokinetic parameters. DLK1-Fc fusion protein has relatively higher stability than non-fusion protein, significantly reduces migration of various cancer cell lines, and provides superior cancer metastasis inhibition effect even at small concentration. Accordingly, DLK1-Fc fusion protein can be used efficaciously as an effective ingredient of a composition for inhibiting cancer metastasis.

Method for inhibiting cancer metastasis by administration of the extracellular domain DLK1 or a DLK1-FC fusion protein

Growing community of inventors

Suwon-si, South Korea

Donghee Lee