Lg Chem, Ltd

Donggyun Kang

Jung Yun Choi

Chul Woong Kim

Hye Ok Kang

In Young Huh

Jae Hyung Kim

Sungwoon Heo

Younghyun Cho

Eungwon Kim

Suhyun Cho

Banseok Choi

Provided is a method for preparing a block copolymer including a step of subjecting a lactide monomer to ring-opening polymerization in the presence of a biosynthesized poly(3-hydroxypropionate) initiator to prepare a polylactide-poly(3-hydroxypropionate) block copolymer.

Method for preparing block copolymer

Provided is a biopolymer composition, a preparation method for the same, and a bioplastic using the same, the biopolymer composition comprising at least 83.5 weight % of a copolymer resin of lactic acid (LA) and 3-hydroxypropionate (3HP), an antioxidant, and a lubricant, and the composition having an elongation percentage of at least 90% but not greater than 500%.

Biopolymer composition, preparation method for same and bioplastic using same

The present invention relates to a novel 3-hydroxypropionate-lactate block copolymer [P(3HP-b-LA)], and a method for preparing same, and more specifically, provides a method for preparing a 3-hydroxypropionate-lactate block copolymer, and a 3-hydroxypropionate-lactate block copolymer produced thereby, the method comprising: a first culture step in which, by using recombinantimproved so as to be incapable of biosynthesizing lactic acid, P(3HP) is biosynthesized at the early stage of culturing by having glycerol as a carbon source and through 3-hydroxypropionate-generating genes and an enhanced PHA synthase; and a second culture step in which P(3HP) production is inhibited by using a carbon catabolic repression system for selectively introducing only glucose intowhen glycerol and glucose are supplied together as carbon sources, and in which polylactate is biosynthesized to an interrupted P(3HP) terminus by the enabling of the expression of a lactate synthase and a lactyl-CoA converting enzyme through an IPTG induction system.

Poly(3-hydroxypropionate-b-lactate) block copolymer using microorganisms

Provided is a lactic acid-based block copolymer which is biodegradable while having excellent mechanical properties.

Block copolymer

Provided are a novel 3-hydroxypropionate-lactate block copolymer [P(3HP-b-LA)], and a method for preparing same, comprising: a) transforming a recombinant microorganism modified to be incapable of biosynthesizing lactic acid with a vector including a 3-hydroxypropionyl-CoA biosynthesis gene and a polyhydroxyalkanoate (PHA) synthetase gene, and a vector including a lactate biosynthesis gene and a gene of an enzyme that converts lactate to lactyl-CoA; (b) synthesizing poly(3-hydroxypropionate) (P(3HP)) by culturing the recombinant microorganism using a glycerol as a carbon source; and (c) inhibiting P(3HP) production by adding IPTG and glucose, and biosynthesizing polylactate (PLA) at the end of P(3HP) synthesized in step (b) by enabling the expression of a lactate biosynthesis enzyme and an enzyme that converts lactate to lactyl-CoA. Also provided is a recombinant microorganism produced in step a).

Growing community of inventors

Daejeon, South Korea

Donggyun Kang