Beijing Hanmi Pharmaceutical Co., Ltd.

Beijing Hanmi Pharm. Co., Ltd.

Dongge Yang

Jiawang Liu

Yaping Yang

Nanmeng Song

Yang Yang

Maengsup Kim

Mengxie Jin

Hongjuan Zhang

The present invention provides a method for production of stable and highly specific heterodimeric immunoglobulin constructs, e.g., bispecific antibodies, retaining desirable properties of native IgG and lacking undesirable heavy chain-light chain mispairing, that can simultaneously bind two target molecules and are more potent in the treatment of complex diseases.

Heterodimeric immunoglobulin constructs and preparation methods thereof

An antibody specifically binding to IL-17A or a functional fragment thereof. The antibody or functional fragment thereof includes an IL-17A chimeric antibody and a functional fragment thereof, and an IL-17A humanized antibody and a functional fragment thereof.

Antibody specifically binding to IL-17A, encoding nucleic acid, and method of using the antibody

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Beijing, China

Dongge Yang