Risen (suzhou) Pharma Tech Co., Ltd.

Suzhou Sinovent Pharmaceuticals Co., Ltd.

Evopoint Biosciences Co., Ltd.

Dongdong Wu

Xianqi Kong

Jiamin Gu

Jiasheng Lu

Xiang Ji

Xiuchun Zhang

Daiqiang Hu

Xinyong Lv

Jinchao Ai

Lin Wang

Gang Chen

Dongqing Zhu

Xiaolin He

Guowei Song

Jun Gu

Xin Li

Yuchuan Wu

Wei Peng

Yonghan Hu

Bin Huang

Xi Chen

Xiao Xi Liu

Shaoqiang Huang

Feng Zhou

Jinlian Zhu

Chengyong Sun

Fan Hu

Jinchao Al

Jun Xian

There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-β related diseases, such as Alzheimer's disease.RRX—CR—CH—CH—SOH   (I)

Isotope-enriched 3-amino-1-propanesulfonic acid derivatives and uses thereof

The present invention provides a novel EZH2 inhibitor compound represented by formula (I) and a use of the inhibitor compound in preventing or treating a disease mediated by EZH2.

Polysubstituted benzene compound and preparation method and use thereof

There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a manual of joint and bone disorders such as arthritis and osteoporosis.

Glucosamine derivatives for the prevention or treatment of joint disorders

There are provided compounds of Formula (A) and pharmaceutically acceptable salts and esters thereof, and pharmaceutical compositions thereof, used for the prevention or treatment in a mammal of joint and bone disorders such as arthritis and osteoporosis.

Glucosamine derivatives and pharmaceutical uses thereof

Disclosed in the present invention are a heterocyclic compound, an application thereof and a pharmaceutical composition comprising the same. Provided by the present invention are a heterocyclic compound represented by formula I or a pharmaceutically acceptable salt thereof. The compound has a novel structure and a good inhibitory activity against autotaxin (ATX). 

Heterocyclic compound, application thereof and pharmaceutical composition comprising same

There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-&#x3b2; related diseases, such as Alzheimer's disease.RRX&#x2014;CR&#x2014;CH&#x2014;CH&#x2014;SOH&#x2003;&#x2003;(I)

CD73 (also known as ecto-5'-nucleotidase) inhibitor compounds are provided, as well as compositions and uses thereof for treating or preventing CD73-associated or related diseases, disorders and conditions, including cancer- and immune-related disorders. CD73 inhibitor compounds include compounds having the structure set forth in Formula I and pharmaceutically acceptable esters or salts thereof. 

CD73 inhibitors and pharmaceutical uses thereof

There are provided isotope-enriched compounds of Formula (I) and pharmaceutically acceptable salts or esters thereof, as well as pharmaceutical compositions thereof and methods of use thereof for prevention and treatment of amyloid-&#x3b2; related diseases, such as Alzheimer's disease.RRX&#x2014;CR&#x2014;CH&#x2014;CH&#x2014;SOH&#x2003;&#x2003; (I)

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Suzhou, China

Dongdong Wu