Chinese Academy of Sciences

Nanjing Tech University

Other

Nanjing University of Technology

Hamlin Electronics (suzhou) Co. Ltd.

Hamlin Electronics (suzhou) Ltd.

Jiangsu Dongbo Bio-pharmaceutical Co. Ltd.

Dong Liu

Yong Chen

Hanjie Ying

Yingjian Wang

Decheng Wu

Chenjie Zhu

Huanqing Niu

Wei Wei

Pingkai Ouyang

Wei Zhuang

Jinglan Wu

Ming Lei

Qingguo Liu

Bin Yu

Chenbo Xie

Zhiqing Zhong

Liyong Qian

Liujun Zhong

Wenju Wang

Pengpeng Yang

Chenglun Tang

Bangxin Wang

Yufei Chu

Aiyuan Fan

Xiaojun Zhou

Zhenzhu Wang

Kunming Xing

Zhiqiang Kuang

Qiang Wang

Ming Li

Yu Wang

Lei Li

Xiao Zhang

Yi Xu

Efrem Fesshaie

Di Zhang

Seong-Jae Lee

Xiaochun Chen

Jingjing Xie

Wei Zhou

Jie Liu

Jianfei Zhao

Paulius Kabisius

Jianxin Bai

Tao Shen

Shengcai Shi

Zhuotao Tan

Xiaoqing Lin

Tao Zhou

Zhenhui Lin

Peicheng Wu

Xiaolei Huang

Guanjie Jiang

Wenfeng Tan

Lingxia Zhong

Taihui Zheng

Qin Zhang

Yaping Fu

Yaoying Han

Tao Gan

Qijun Yao

Zhengguo Ling

Xingyuan Cao

Jungiang Shan

Wenying Duan

Mingbin Zheng

Yupeng Yan

An Li

Yadong Lu

Wenan Deng

Jiashun Zhou

An Ma

Chunxu Meng

Cungui Men

Guohe Que

Zongxian Wang

Yuhan Yang

Baoquan Mu

Chenguang Liu

Shishi Wu

Shichang Liang

Xiwei Peng

Bin Shi

A cordycepin-based derived compound with an anti-tumor effect, and a structure of the compound is as shown in formula I; a cordycepin derivative and a pharmaceutical composition thereof provided by the invention have a good anti-tumor proliferation effect; compared with a parent drug, the cordycepin derivative has better affinity to cell membranes, so that a half-life period of in-vivo metabolism of the drug is longer, and in-vivo remaining time of the drug is longer; compared with other nucleoside anti-tumor drugs, the cordycepin derivative and the pharmaceutical composition thereof provided by the invention have wider types and action ranges of tumors, have excellent inhibition effects on a gastric cancer, a pancreatic cancer, a liver cancer, a small cell lung cancer, a colorectal cancer, melanoma, an ovarian cancer and the like, and have lower side effects and better curative effects.

Cordycepin-based derivatized compound with anti-tumor effect

A method for preparing a nitrogen-containing heterocyclic compound and a derivative thereof by an enzymatic-chemical cascade method, comprising: reacting an alcohol, an amine, an alcohol dehydrogenase, a flavin molecule and a coenzyme in a solvent to obtain the nitrogen-containing heterocyclic compound and the derivative thereof; compared with the prior art, the method is a green and economical enzymatic-chemical cascade method, and is used for synthesizing nitrogen-containing heterocyclic compounds and derivatives thereof; compared with a common toxic chemical catalyst, the alcohol dehydrogenase is selected as a catalyst in the method, which has the characteristics of high substrate specificity, no pollution, high catalytic efficiency, no toxic solvents and simple post-treatment.

Method for preparing nitrogen-containing heterocyclic compound and derivative thereof by enzymatic-chemical cascade method

An omnidirectional measurement system for a time-varying characteristic of atmospheric vapor radiation includes an antenna and calibrator assembly, a receiver assembly, a room temperature IF assembly, and a data acquisition and system control assembly. Atmospheric vapor features a wide profile and strong radiation in a frequency band of 183 GHz, and is often seen in the characteristic measurement of atmospheric vapor in high-altitude areas. The omnidirectional measurement system combines a superconductor-insulator-superconductor (SIS) mixer with high detection sensitivity in the frequency band of 183 GHz with a structure that integrates pitch scanning, omnidirectional scanning, and automatic calibration to achieve fast and high-precision omnidirectional scanning measurement of the time-varying characteristic of atmospheric vapor radiation. The omnidirectional measurement system has a pitch adjustment-based fast omnidirectional scanning function, and can measure the time-varying characteristic of atmospheric vapor radiation with higher precision and higher temporal resolution through the SIS mixer with higher sensitivity.

Omnidirectional measurement system for time-varying characteristic of atmospheric vapor radiation

The invention relates to the technical field of radar detection, in particular to a device for real-time detection of spectrum from airborne hyperspectral imaging LiDAR and method thereof. The device comprises a laser and a reference module; the reference module comprises a first reflecting mirror and a second reflecting mirror with a given transmittance; the first reflecting mirror and the second reflecting mirror are arranged with a focusing mirror and an optical fiber in sequence therebetween. The laser emits a laser light to the first reflecting mirror with a given transmittance, and the beam of the laser light transmitted through the first reflecting mirror after passing the focusing mirror is used as the reference beam after passing the optical fiber. The invention enables detection of the spectral line of each pulse and improves the precision of reflection spectrum of the ground object measured by the system.

Device and method for real-time measuring the spectrum of airborne hyperspectral imaging LiDAR

This application relates to a device for measuring a transmittance curve of an Fabry-Perot using a frequency comb light source and a method using the same. The device includes the following components sequentially arranged in an optical path: a single frequency pulse laser generating single frequency pulse laser; a frequency comb laser converting received single frequency pulse laser into frequency comb laser; and an Fabry-Perot to be detected receiving laser output from the frequency comb laser; where the device further includes a first receiving unit receiving laser from an output end of the frequency comb laser and performing component and spectrum analysis, and a second receiving unit receiving laser from an output end of the Fabry-Perot to be detected and performing component and spectrum analysis.

Device for measuring transmittance curve of Fabry-Perot using frequency comb light source and method using the same

The invention relates to the technical field of radar detection, in particular to a method for radiation calibration of airborne hyperspectral imaging LiDAR system. The method comprises the following steps: S1. A monochromator in a spectrum calibration system emits optical signals of different spectrum values to scan the radar system, thus to obtain the bandwidth and central wavelength of each channel in the radar system; S2. According to the return signal power P(λ, z) in the hyperspectral LiDAR equation and the optical power P(λ) received by the target surface of the detector in the radar system under experimental conditions, a white diffuse reflection board is taken as the ground object target, and a ranging channel is used to measure the flying height of the radar system, thus to obtain the parameters in the return signal power P(λ, z) and the reflection spectrum β(λ).

Method for radiation calibration of airborne hyperspectral imaging LiDAR system

The present application discloses the use of diatom in rice planting and a cultivation method of rice in symbiosis with diatom and relates to the technical field of rice planting. The use of diatom in rice planting is achieved by adding diatom to an irrigated paddy field and performing co-cultivation during rice planting. Co-cultivation of diatom and rice can effectively achieve the beneficial effects of increased yield/silicon, thicker straw, and increased lodging resistance in rice, and can reduce soil degradation, reduce the risk of heavy metal pollution and increase soil fertility.

Use of diatom in rice planting and cultivation method of rice in symbiosis with diatom

Disclosed is a device and a method for measuring Fabry-Parot (FP) transmittance curve by using a whispering gallery mode laser source. The device includes: a seed laser, a first polarizer, a second polarizer, a spectroscope, a beam reduction system, a lens, and Polydimethylsiloxane (PDMS) microfluidic chip arranged in sequence.

Device and method for measuring transmittance curve of Fabry-Parot using whispering gallery mode laser source

The invention discloses a recombinantfor producing lysine by biofilm continuous fermentation and a construction method thereof, wherein the recombinantis constructed by overexpressing a protease gene FtsH in a; and the construction method comprises the following steps of: (1) performing PCR on a genome of the, and amplifying the FtsH gene to obtain an amplified FtsH gene segment; (2) cloning the FtsH gene segment to an overexpression plasmid to obtain a recombinant plasmid; and (3) introducing the recombinant plasmid into the, and screening to obtain the recombinant. The invention has the beneficial effects that thefor overexpressing the protease FtsH is constructed in the invention, and a film-forming ability of theis enhanced, such that a yield of continuous immobilized fermentation of theis increased by 38.2% than that of free fermentation of an original bacterium, and a fermentation cycle is shortened by 26.4%.

Recombinant corynebacterium glutamicum for producing lysine by biofilm continuous fermentation and construction method thereof

The invention discloses a method for producing lysine by utilizing adsorption and immobilized fermentation of a recombinant, wherein the recombinantis constructed by simultaneously overexpressing an adenosine triphosphate ATPase while knocking out an extracellular nuclease ExeR in a. The recombinantcan effectively improve eDNA secretion of theand reduce eDNA degradation of the, so that thecan be more easily adsorbed on a surface of a solid carrier for immobilized fermentation, such that a yield of continuous immobilized fermentation of theis increased by 49.67% than that of free fermentation of an original bacterium, and a fermentation cycle is shortened by 29.17%.

Method for producing lysine by utilizing adsorption and immobilized fermentation of recombinant corynebacterium glutamicum

An ignitor for an electronic detonator, the ignitor including a microcontroller and a capacitor mounted on a printed circuit board (PCB) and electrically connected to one another, the microcontroller configured to discharge the capacitor in response to an actuation signal received by the microcontroller, a pair of conductive traces extending from the capacitor, a resistive element extending between the conductive traces and configured to radiate heat in response to current flowing therethrough, and a shroud disposed over the resistive element, the shroud containing a pyrotechnic composition that at least partially covers the resistive element.

Ignitor for electronic detonator

A rotary position sensor () may include a sensor housing () defining an interior cavity. A first rotor () may be positioned and rotatable within the interior cavity, the first rotor () including a first magnet (). Furthermore, the rotary position sensor () may include a second rotor () positioned and rotatable within the interior cavity, the second rotor () including a second magnet (). The first magnet () may include a first shielding member () associated with a surface of the first magnet (), and the second magnet () may include a second shielding member () associated with a surface of the second magnet (). The first shielding member () may face the second shielding member ().

Rotary position sensor with dual magnet arrangement

It discloses a lignin enhanced wood-plastic composite, belonging to the field of polymer based composites. The wood-plastic composite is composed of one or more of plant fiber, lignin, a recycled thermoplastic plastic, mineral powder and a processing aid, and is processed by a screw granulating extrusion process. Compared with the prior art, the mechanical properties, heat stability and aging resistance of a wood-plastic material are improved by adding lignin into the wood-plastic material according to the present invention.

Lignin enhanced wood-plastic material and preparation method thereof

A reagent for detection of urine monophenolic metabolites and a method for preparing the reagent are disclosed, in which the monophenolic metabolites, for example, tyrosine, p-hydroxyphenyl alanine, tryptophan and 5-hydroxyindoleacetic acid can serve as tumor markers. The reagent for detection of urine monophenolic metabolites is an aqueous solution containing nitric acid, sulfuric acid, mercuric sulfate, mercurous nitrate, nickel nitrate, phosphomolybdic acid and cobalt sulfate. The preparation method includes preparation of solutions A, B, C, D and E, and mixing. The subject matter allows easy availability of raw materials, low cost, a simple preparation process, obtainment of reagents with stable performance which offer the advantages including high versatility, high sensitivity and good specificity when used in cancer detection, a simple detection process, a short detection cycle and easy determination, and is particularly suitable for large population screening, assistance in clinical cancer diagnosis and dynamic follow-up.

Monohydroxyphenyl metabolite urine detection reagent and preparation method thereof

The present invention providesand an application thereof. A preservation number of theprovided in the invention is CGMCC No. 5234. Theprovided in the present invention can be used for cogeneration of acetone, butanol, ethanol, and 3-hydroxy butanone through fermentation, so as to improve the economic benefit of butanol fermentation. NAD+ coupling and regeneration can be implemented by adding metabolism or growth regulating substances, so as to improve the product yield, and at the same time, the yield of cogeneration products can be flexibly adjusted, so as to cater for the market demand.

Clostridium acetobutylicum and application thereof

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Jiangsu, China

Dong Liu