Cj Corporation

Cj Cheiljedang Corporation

Korea University Research and Business Foundation

Korea Research Institute of Chemical Technology

Snu Rdb Foundation

Dong Kwon Lim

Yong Sik Youn

Kwang Hyeg Lee

Choong Sil Park

Seong Hwan Cho

Young Hoon Kim

Kyung Mi Park

Sung Hak Jung

Kyu Jeong Yeon

Sung Hak Lee

Hae Tak Jin

Hyun Suk Kang

Yun Taek Jung

Hea Ran Suh

Hyuk Koo Lee

Yun Cheul Kim

Jun Hee Cheon

Kwang Do Choi

Chang Ju Kim

Eun Young Yang

Eun Ju Jeong

Jae Kyoung Ko

Il Hwan Cho

Myeong Yun Chae

Seog Beom Song

Sang Yup Lee

Seungwoo Lee

Jae Won Lee

Dong June Ahn

Jwa Min Nam

Yung Doug Suh

Ki Seok Jeon

The present invention provides a a nanostructure which includes: a core comprising one or more planes configured to come into planar contact with at least one plane of an ice crystal; and an oligopeptide which is conjugated to at least one plane of the core and comprises (Thr)-, (Ala)-, (Ser)-, or (Gly)-, wherein the nanostructure is a polyhedron-shaped nanostructure present in water in a colloidal form to control freezing, and n is an integer of 2 to 7.

Anti-freezing composition comprising gold nanoparticle with peptide

The present invention is to provide a nanoparticle, which can be used effectively for Raman analysis based on very high amplification effect of electromagnetic signal by plasomonic coupling of nanogap formation inside thereof and high reproducibility, and which includes core and surrounding shell with nanogap formation between the same and the method of synthesis thereof. The present invention is also to provide the method for detecting the analyte using the above nanoparticle and the analyte detection kit including the above nanoparticle.

Single nanoparticle having a nanogap between a core material and a shell material, and preparation method thereof

Disclosed is a method for the separation of S-(&#x2212;)-amlodipine from a racemic amlodipine. Featuring the use of inexpensive L-tartaric acid as an optical resolution agent and DMAC as a solvent, the separation method allows the resolution of S-(&#x2212;)-amlodipine from racemic amlodipine at high yield and to a satisfactory enantiomeric excess and thus is economically favorable and applicable to the mass production of the optical isomer.

Method for the separation of S-(&#x2212;)-amlodipine from racemic amlodipine

Disclosed are crystalline S-(&#x2212;)-amlodipine adipic acid salt anhydrous and a preparation method thereof. The crystalline S-(&#x2212;)-amlodipine adipic acid salt anhydrous exhibits excellent physical and chemical properties including non-hygroscopicity, solubility, thermal stability, and photostability, and is superior in formulation processability and long-term storage safety.

Crystalline S-(&#x2212;)-amlodipine adipic acid salt anhydrous and preparation method thereof

Disclosed are novel inorganic acid salts of sibutramine, which have good physicochemical properties, and crystalline forms thereof. Also disclosed are pharmaceutical compositions comprising the compounds as effective ingredients, methods of preparing the compounds, and the use of the compounds.

Inorganic acid salts of sibutramine

Disclosed is a novel sulphonic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Sulphonic acid salt of sibutramine

Disclosed is a novel dicarboxylic acid salt of sibutramine, which has good physicochemical properties. Also disclosed are a method of preparing the compound and a pharmaceutical composition comprising the compound.

Dicarboxylic acid salt of sibutramine

Provided is a method of preparing an optically pure compound having formula 1 or its salts. The method includes: reacting (R)-2-(4-methoxy-3-aminosulfonyl-phenyl)-1 -methylethylamine or its salts with a compound selected from the group consisting of chloroacetic acid, bromoacetic acid, fluoroacetic acid, iodoacetic acid, &#x3b1;-halogenoacetic acid anhydride, and &#x3b1;-halogenoacetyl halide in the presence of a base or an acylating agent.

Method of preparing optically pure phenethylamine derivatives

A novel crystalline organic acid salt of amlodipine having improved physiochemical properties, a preparation method thereof and a pharmaceutical composition comprising the same are provided.

Crystalline organic acid salt of amlodipine

Disclosed are a novel organic acid salt of amlodipine, its preparation method, and a pharmaceutical composition containing as a therapeutically active ingredient the same.

Organic acid salt of amlodipine

Disclosed are a novel organic acid salt of amlodipine, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.

Disclosed are a novel organic acid salt of amlodipine with superb physicochemical properties, its preparation method, and a pharmaceutical composition containing the same as a therapeutically active ingredient.

Growing community of inventors

Gyeonggi-do, South Korea

Dong Kwon Lim