Jinwoo Bio Co., Ltd.

Other

Dong Keon Kweon

Seung Hyeon Park

Joo Yeon Hong

Seul Ki Kim

Young Chan Jeon

Young Mo Lee

Seung Taik Lim

Ji Hyun Bang

Da Wei Li

Man Ha

Myoung Han Lee

Sin Hwan Kwon

Jong Soo Kim

So Mang Choi

Hyun Ho Lee

A high-strength hyaluronate fiber, suitable for use in a surgical suture, a lifting thread, a tissue-engineering scaffold, etc., and a manufacturing method thereof are proposed. The method includes (a) controlling a water content of a hyaluronate having a weight average molecular weight of 100-3,000 kDa to 50-95 wt % to prepare a hyaluronate paste, (b) melting the hyaluronate paste having a controlled water content at a temperature ranging from room temperature to 100° C., and then extruding the hyaluronate paste through a nozzle, and (c) drying the extruded spinning fluid to form a fiber. The hyaluronate fiber has the water content of 5-25 wt %, the tensile strength of 3 to 15 kg/mm, and a smooth surface with small cracks, so that the hyaluronate fiber can be used for a surgical suture, a lifting thread, a filler for cosmetic surgery, a tissue-engineering scaffold, etc.

Hyaluronate fiber and manufacturing method thereof

Provided is a method of manufacturing a hyaluronate-coated high-functional suture and a high-functional suture manufactured thereby, and more particularly to a method of manufacturing a high-functional suture and a high-functional suture manufactured thereby, wherein a suture for internal and external surgery derived from a conventional chemical synthetic material is coated with a hyaluronate as a biocompatible material, thus improving biocompatibility, functionality and ease of use. Upon application of the hyaluronate-coated suture of the invention to the human body, the hyaluronate applied on the surface of the suture is rapidly swollen by body fluids and can thus function as a lubricant, thus being convenient to use by a surgical doctor and reducing the pain of a patient and maximizing the functions of skin filling or skin regeneration in the body.

Method for preparing high-functional suture yarn coated with hyaluronate and high-functional suture yarn prepared therefrom

The present invention relates to a method of manufacturing a hyaluronate film and a hyaluronate film manufactured thereby, and more particularly to a method of manufacturing a hyaluronate film through a solvent-casting process or using an automatic film applicator that facilitates mass production and to a hyaluronate film manufactured thereby, which is useful as a mask pack for cosmetics, a patch for medicaments and medical devices, a film-type adhesion inhibitor, etc. Unlike conventional liquid products, the hyaluronate film according to the present invention has a dry surface and thus entails no concern about microbial contamination, is easy to produce/manage/distribute/use, and has superior mechanical properties, whereby it can be utilized for various applications such as packs, patches, artificial skin and the like for cosmetics, medicaments, and medical devices.

Method for manufacturing hyaluronate film, and hyaluronate film manufactured thereby

Provided is a hyaluronate fiber, and more particularly to a hyaluronate fiber, suitable for use in a surgical suture, a filler for cosmetic surgery, a lifting thread, a tissue-engineering scaffold, etc., and a method of manufacturing the same. Further, a method of manufacturing the hyaluronate fiber through melt spinning is provided, which includes (a) controlling the water content of a hyaluronate having a weight average molecular weight of 500&#x2dc;3,000 kDa to 5&#x2dc;20%, (b) producing a hyaluronate fiber by placing the hyaluronate having a controlled water content in a melt-spinning apparatus and performing heating to 150&#x2dc;200&#xb0; C. and then high-pressure spinning, and (c) hardening the surface of the hyaluronate fiber by immersing the hyaluronate fiber in an ethanol aqueous solution.

Method for manufacturing hyaluronate fibers by using melt spinning and hyaluronate fibers manufactured thereby

Provided are a method of manufacturing a hyaluronate-coated high-functional suture and a high-functional suture manufactured thereby, and more particularly to a method of manufacturing a high-functional suture and a high-functional suture manufactured thereby, wherein a suture for internal and external surgery derived from a conventional chemical synthetic material is coated with a hyaluronate as a biocompatible material, thus improving biocompatibility, functionality and ease of use.

Growing community of inventors

Yongin-si, South Korea

Dong Keon Kweon