Amorepacific Corporation

The Green Cross Corporation

Dong Hyuk Jang

Hyun Yeul Lee

Yong Jin Kim

Kisoo Park

Hee Jeong Seo

Min Ju Kim

John Hwan Lee

Kwang-Seop Song

Eun-Jung Park

Soongyu Choi

Hyoung June Kim

Mi-Soon Kim

Lee Kyoung Kwon

Younggyu Kong

So Ok Park

Ga Young Cho

Sung-Wook Choi

Man-Young Cha

Ickhwan Son

Dong-Hyun Paik

Sang-ho Ma

Jangwon Hong

Sang Mi Kang

Hae Jin Jung

Sang Hoon Han

Sung Il Park

Chang Hoon Park

Hwa Young Shin

Hyun Suk Lee

The present disclosure relates to an external-use skin preparation composition containing a natural ceramide, a ceramide derivative, and aextract, and more specifically, the present disclosure relates to an external-use skin preparation composition containing these ingredients, thereby being effective for enhancing skin moisturizing ability, reducing skin wrinkles, and enhancing elasticity. In addition, the present disclosure relates to use of the composition, and a method for improving skin moisturization, reducing skin wrinkles, and/or improving skin elasticity by using the composition.

Composition for external application containing a ceramide, a derivative thereof and an extract of

The present invention relates to a composite powder of jade powder and a porous polymer, and more specifically relates to a composite powder (jade sphere) in which jade powder particles are impregnated in a porous polymer, the composite powder being produced by spraying, in one step, a dispersion in which jade powder has been dispersed in a solution that dissolves porous polymers, and to a cosmetic composition containing the composite powder, and to a manufacturing method for the composite powder.

Composite powder in which jade powder particles are impregnated in porous polymer, cosmetic composition containing same and manufacturing method for same

Provided is pyrazole derivatives as a TNIK (Traf2- and NCK-interacting kinase), IKK&#x3b5; (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor; the pyrazole derivative according to the present invention effectively inhibits TNIK, IKK&#x3b5; and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

Pyrazole derivatives as TNIK, IKK&#x3f5; and TBK1 inhibitor and pharmaceutical composition comprising same

Provided are 7-azaindole or 4,7-diazaindole derivatives as an IKK&#x3b5; (I-kappa-B kinase epsilon) and TBK1 (TANK-binding kinase 1) inhibitor. The 7-azaindole or 4,7-diazaindole derivative effectively inhibits IKK&#x3b5; and TBK1, and thus is useful not only as an anticancer agent for the treatment of various cancers including colorectal cancer, breast cancer, CNS cancer, colon cancer, non-small cell lung cancer, kidney cancer, prostate cancer, ovarian cancer, uterus cancer, stomach cancer, liver cancer, skin cancer, lung cancer, brain cancer, bladder cancer, esophageal cancer, pancreatic cancer, thyroid cancer, head and neck cancer, squamous cell carcinoma, osteosarcoma, B-cell or T-cell lymphoma, acute or chronic leukemia and multiple myeloma, but as a therapeutic agent for chronic inflammation.

7-azaindole or 4,7-diazaindole derivatives as IKK&#x3f5; epsilon and TBK1 inhibitor and pharmaceutical composition comprising same

A cosmetic composition according to the present invention may prevent the precipitation of caffeine at a low temperature, and thus may comprise a high concentration of caffeine that is effective in promoting lipolysis. Caffeine is known to promote lipolysis when applied to a human body. The cosmetic composition of the present invention may comprise a high concentration of caffeine, and thus can be valuably use in cosmetics or the like that requires effects of caffeine such as slimming effects, effect of relief from facial swelling or the like.

Cosmetic composition comprising high concentration caffeine and niacinamide

Growing community of inventors

Yongin-si, South Korea

Dong Hyuk Jang