Korea Institute of Science and Technology

Bioinfra Life Science Inc.

Pacific System Co., Ltd.

Dong Hee Park

Won Kook Choi

Jong Ho Won

Chul Woo Kim

Dong Ick Son

Hea Ry Oh

Sang Yub Ie

Dong Soo Lee

Ji Won Choi

Won-Kook Choi

Do Kyung Hwang

Chang Hwan Wie

Ji Hwan Kim

Chui Woo Kim

Byoung Wook Kwon

In Seok Park

Dong Ik Son

Disclosed are a method for increasing the viability of cells by ultrasound irradiation and an ultrasound irradiation apparatus using same. The method comprises: applying a drug and an epidermal drug delivery system onto the epidermis of a subject; and, with ultrasound parameters each being preset within a certain range, an ultrasound irradiation apparatus irradiating ultrasound onto the epidermis of the subject through an ultrasound generation unit placed within a critical range from the epidermis of the subject, wherein the epidermal drug delivery system induces the formation of cavities, i.e., cavitation around the epidermis of the subject when the ultrasound is irradiated, the ultrasound parameters at least include an ultrasound pressure and an ultrasound duty percentage, the ultrasound pressure is 0.5-1 MPa, and the ultrasound duty percentage is 1-5%.

Method for increasing cell viability by using drug delivery system and ultrasound irradiation, and ultrasound irradiation apparatus using same

Disclosed are a method for increasing the viability of a cell by irradiating the cell with ultrasonic waves, and an ultrasound irradiation apparatus using same, wherein in a state where each of ultrasonic parameters is preconfigured in a predetermined range, the ultrasonic irradiation apparatus places an ultrasonic generation unit within a threshold range from the epidermis of an object to irradiate the epidermis of the object with ultrasonic waves, the ultrasonic parameters include at least a pressure of ultrasonic waves and a duty percentage of the ultrasonic waves, the pressure of the ultrasonic waves is 0.5 MPa to 1 MPa, and the duty percentage of the ultrasonic waves is 1% to 5%.

Method for increasing viability of cell by irradiating cell with ultrasonic waves and ultrasonic irradiation apparatus using same

Provided are a method for preparing liposomes comprising ultrasound reactive microbubbles for drug delivery, comprising (a) a step of producing ultrasound reactive microbubbles comprising an inert gas therein and having a first shell formed on the outer surface thereof, followed by forming a uniform size distribution of the ultrasound reactive microbubbles through an extruder; and (b) a step of producing liposomes comprising the ultrasound reactive microbubbles distributed in a uniform size and a medicament therein and having a second shell formed on the outer surface thereof, followed by forming a uniform size distribution of the liposomes through an extruder; and a liposome using same.

Method for preparing liposome comprising ultrasound reactive microbubble for drug delivery and liposome using same

Provided are an anti-reflection nano-coating structure and a method of manufacturing the same. The anti-reflection nano-coating structure has low dependency on incident light. The anti-reflection nano-coating structure has a normal-align nano-structure on the entire surface of the substrate regardless of curvature of the substrate by controlling a ratio of reactive gas during sputtering.

Anti-reflection nano-coating structure

Disclosed are methods for preparing pure graphene using chemical bonding between graphite oxide and metal oxide nanoparticles, and graphene and nanoparticles having a quasi metal oxide-graphene core-shell prepared therefrom. The disclosed methods for preparing graphene allow chemical bonding and separation through a simple acid treatment process using inexpensive materials. Also, because the reaction can be carried out at low temperature, the processing cost is low. And, pure graphene with few impurities can be prepared quickly in large scale.

Method for producing graphene by chemical exfoliation

The present invention relates to an integrated, composite hybrid electric device in which various devices are formed as a single unit on one flexible substrate, and a fabrication method thereof. More particularly, the present invention a hybrid electric device in which a display device, a vibration-generating (or vibration-sensing) device, and a non-volatile memory device are formed on a single flexible piezoelectric polymer substrate into a single unit by using a flexible piezoelectric polymer substrate whose both surfaces are thinly deposited with a patterned transparent oxidation electrode, and a fabrication method thereof.

Hybrid electric device using piezoelectric polymer substrate

The present invention relates to an AC voltage-driven light emitting device having a single active layer of a core-shell structure (p-i-n structure) in which intrinsic semiconductor nanocrystals, exciton combination centers, are uniformly and isotropically distributed around p-type polymer particles, and n-type small molecular particles surround the semiconductor nanocrystals and p-type polymer, and a manufacturing method thereof. An active layer of a core-shell structure using a polymer-semiconductor nano hybrid in the light-emitting device has an inversion symmetry characteristic showing the same current-voltage characteristic during application of a voltage in a forward direction and a reverse direction. Therefore, due to this inversion symmetry characteristic, the light emitting can be driven by even an AC voltage. Also, since the device can be driven by an AC voltage, limitations of an existing DC voltage-driven organic light emitting diode, that is, destruction or a defect of the device by an overcurrent and generation of a dark spot by degradation of local constituent organic materials are solved.

Growing community of inventors

Seoul, South Korea

Dong Hee Park