Syntex (u.s.a.) Inc.

Roche Palo Alto LLC

Donald Roy Hirschfeld

Zachary Kevin Sweeney

James Patrick Dunn

Tania M Silva

Harit Vora

Denis John Kertesz

John O Link

David Bernard Smith

Francisco Xavier Talamas

Leyi Gong

John J Nestor, Jr

Gary A Peltz

Robert Stephen Wilhelm

Paula Nanette Belloni

David Berard Smith

The present invention provides compositions for treating an HIV infection comprising administering a compound according to formula I where Ar, R-R, Rand Xare as defined herein with at least one carrier, excipient or diluent. 

Methods for treating retroviral infections

The present invention provides compounds for treating or preventing an HIV infection, or treating AIDS or ARC comprising administering a compound according to formula I where Ar, R-R, Rand Xare as defined herein. 

The present invention provides compounds for treating or preventing an HIV infection, or treating AIDS or ARC comprising administering a compound according to formula I where Ar, R&#x2014;R, R, R, R, R&#x2014;R, X, Xm, n, o and p are as defined herein 

Non-nucleoside reverse transcriptase inhibitors

Cyclic amine derivatives-CCR-3 receptor antagonists

Piperidine quaternary salts- CCR- 3 receptor antagonists

This invention provides novel cationic lipids, particularly guanidino lipids, and methods for their preparation. Also provided are polyanionic-lipid complexes comprising the lipids of the invention, their preparation and use to deliver biologically active substances, particularly nucleic acids to cells.

Cationic lipids for gene therapy

This invention relates to compounds of the formula: ##STR1## wherein A is biphenyl unsubstituted or substituted on one or both rings with one or more halo, lower alkyl, lower alkoxy or trifluoromethyl substituents; Z is ethylene unsubstituted or substituted with a single lower alkyl substituent or propylene unsubstituted or substituted with one or two lower alkyl substituents; and the pharmaceutically acceptable acid addition salts thereof. These compounds have anticonvulsant activity.

Substituted N-alkyl imidazoles to treat convulsions

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Mountain View, CA, United States of America

Donald Roy Hirschfeld