Southern Research Institute

Atrix Laboratories, Inc.

Stolle Research & Development Corporation

Carson Products Company

Keraplast Technologies, Ltd.

US Government As Represented by the Secretary of the Army

Sharpoint L.p.

Other

Burroughs Wellcome Co.

The University of Alabama

National Patent Development Corporation

Duzitall Equipment Corporation

Donald R Cowsar

Richard L Dunn

James Perry English

David P Vanderbilt

Lee R Beck

Albert C Tanquary

Charles F Flowers, Jr

David D Vanderbilt

Thomas R Tice

Thomas J Laughlin

Danny H Lewis

Thomas A Davis

Mario J De La Guardia

Robert A Casper

Keith Edward Branham

Richard N Terry

Tony R Adair

Albert Charles Tanquary

Steadman D Harrison, Jr

Compositions containing biologically active peptides are disclosed. Active peptides are isolated fragments derived from human hair or sheep wool keratin proteins. Compositions may be prepared for pharmaceutical or topical administration or for use in cosmetic preparations.

Bioactive keratin peptides

Useful materials are produced from keratin containing raw materials by a process that includes gentle lanthionization of cystine disulfide bonds. Hydratable materials are produced for use in medical and cosmetic applications.

Gentle process for conversion of cystine in keratin-containing materials to lanthionine

A biodegradable polymer is provided for use in providing syringeable, in-situ forming, solid biodegradable implants for animals. The polymer is placed into the animal in liquid form and cures to form the implant in-situ. A thermoplastic system to form said implant comprises the steps of dissolving a non-reactive polymer in biocompatible solvent to form a liquid, placing the liquid within the animal, and allowing the solvent to dissipate to produce the implant. An alternative, thermosetting system comprises mixing together effective amounts of a liquid acrylic ester terminated, biodegradable prepolymer and a curing agent, placing the liquid mixture within an animal and allowing the prepolymer to cure to form the implant. Both systems provide a syringeable, solid biodegradable delivery system by the addition of an effective level of biologically active agent to the liquid before injection into the body.

Biodegradable in-situ forming implants and methods of producing the same

Methods for preparing hair relaxer compositions which comprise a lithium salt and an alkaline earth hydroxide, wherein the lithium salt is in molar excess to the alkaline earth hydroxide. Compositions, kits containing the compositions, and methods for using the compositions are also disclosed.

Hair relaxer compositions and methods for preparing same

The present invention relates to a two-component hair relaxer system comprising (a) a first component comprising a cream base containing a water-soluble salt of a relatively strong base with an anion capable of being precipitated by an alkaline earth metal ion under highly alkaline conditions, and (b) a second, separate component, which is substantially free of water, and containing an alkaline material having an alkaline earth metal ion which forms a precipitate with the anion when the first component and second component are mixed.

Hair relaxer compositions

Biodegradable in-situ forming implants and methods for producing the same

An improved method of producing a reservoir device having a rate-controlling membrane and zero-order (constant) release of an agent is provided. A core is sprayed with a solution having a polymer and a solvent, the solvent having a first component which is a rapidly evaporating, low-boiling-point first solvent and a slowly evaporating, high-boiling-point second solvent.

Method of producing zero-order controlled-released devices

Biodegradable polyamides, useful as absorbable sutures and as controlled release binder materials, are prepared by condensing 4,4'-spirobibutyrolactone with a primary diamine, optionally in the presence of a nylon salt, leading to homopolymers containing lactam structural units, or to random copolymers.

Biodegradable polyamides for providing a controlled release therapeutic

Biodegradable polyamides, useful as absorable sutures and as controlled release binder materials, are prepared by condensing 4,4'-spirobibutyrolactone with a primary diamine, optionally in the presence of a nylon salt, leading to homopolymers containing lactam structural units, or to random copolymers.

Biodegradable polyamides

Growing community of inventors

Birmingham, AL, United States of America

Donald R Cowsar