Ortho Diagnostic Systems Inc.

Donald M Davies

Kathleen J Reis

Thomas M Setcavage

Edward J Mazur

Linda J Davis

David J Olekna

Milan Jorik

Walter Milchanoski

Diane E Bechtold

Shelby J Hall

A vessel for conducting blood cell agglutination assays is disclosed. A barrier retains reactants in an upper chamber during incubation, then, in response to a force, permits reagents to enter a lower chamber containing a matrix for separating agglutination.

Foil sealed cassette for agglutination reactions and liner therefor

Agglutination reaction and separation vessel

A device is described for preparing a standardized concentration of washed particles suspended in a fluid. The preferred method is directed to the preparation from whole blood specimens of a standardized concentration of washed red cells in isotonic solution using a device comprising a test tube formed at the bottom end with a nipple-like receptacle having a predetermined volumetric capacity. Whole blood is mixed with isotonic solution in the device which is then centrifuged causing the red cells to be first washed and then packed into the receptacle. The liquid contents of the device are then decanted without disturbing the packed red cells. Thereafter, the red cells are reconstituted to the desired concentration by adding isotonic solution to a predetermined level in the tube and mixing the cells into the isotonic solution.

Particle washing and separation method

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Raritan, NJ, United States of America

Donald M Davies