Marquest Medical Products, Inc.

Other

Emde Corporation

Donald L Bailey

Charles D Williams

A pledget of biological material of predetermined unit dosage is formed by a lyophilizing process. The lyophilizing process involves establishing a specific batch volume of sterile water, dissolving a preestablished amount of biological material in the batch volume of water, filling at least one container with a portion of the solution of water and dissolved material, and lyophilizing the solution in the container into the pledget. The amount of biological material to be dissolved in the water is established in relation to the volume and number of containers, the desired predetermined unit dosage of each pledget, and the desired number of pledgets to be formed at a time.

Lyophilizing and forming biologicals having a predetermined unit dosage

A syringe device has a hollow tubular body that receives a plunger, having in combination a handle portion rotatable within a sealing member portion, for obtaining gas-free blood samples. After an interior chamber of the syringe body is filled with blood under the influences of an individual's blood pressure, a seal is selectively established to isolate the sample. The syringe body is open at one end to receive the plunger and frictionally receives a hypodermic needle through a cylindrical end element disposed at the other end. A pair of linearatly extending seal interrupters, sliced from the handle portion of the plunger, extend from a position fixed on the handle portion across the sealing member to establish breach points, which in turn allow air communication between the interior chamber and the atmosphere. A pair of grooves disposed longitudinally near the open end of the syringe body retain the seal interrupters and prevent permanent indentations from forming in the sealing member while in storage.

Syringe device with means for selectively isolating a blood sample after

A syringe device has a hollow tubular body that receives a resilient sealing member rotatably connected to a hollow plunger. A vacuum pump is connected through a flexible tube to the hollow plunger to thereby withdraw blood using the vacuum created. Once in the syringe body, blood is automatically exposed to an anti-coagulant stored within the syringe body. The anti-coagulant is in flake form and premanufactured from a heparin solution which is allowed to evaporate on a non-stick surface.

Vacuum assisted anti-coagulant syringe device for taking blood samples

A syringe is disclosed for taking blood samples which includes a tubular body, a plunger, a sealing member and a needle. The plunger and sealing member in combination are slideably received in the tubular body with the plunger receiving the sealing member for rotational movement about its longitudinal axis. The sealing member has two longitudinally spaced circumferential sealing locations with a cylindrical space between the sealing locations. Two closeable openings through each seal location are established in the sealing member at 180.degree. opposition to each other by a thread extending across each seal. The thread is attached to the plunger so that after blood passes through the seal nearest the needle end of the syringe, the plunger can be rotated to remove the thread from both seal locations thereby sealing the blood sample in the tubular body after all gases have been purged from the tubular body.

A hollow capillary tube or cartridge is received within the interior of a hollow tubular syringe-like device to collect a blood sample. A fluid inlet means of the capillary cartridge connects in a fluid conductive relationship with a hypodermic needle attached to the syringe-like device to conduct a blood sample to the interior of the capillary cartridge. A fluid outlet means of the capillary cartridge allows the blood sample to fill the capillary cartridge by expelling air from the interior of capillary cartridge. The fluid outlet means includes a removable piece of fluid conductive fibrous material which allows the air to escape as the blood sample is received and which conducts a small amount of blood sample when the capillary cartridge is completely filled. Means for creating a pressure less than ambient pressure at the fluid outlet means of the capillary cartridge may be employed when the arterial blood pressure of the individual from whom the blood sample is collected is less than sufficient to naturally fill the interior of the capillary cartridge. Crystalline heparin deposited on the interior of the capillary tube prevents clotting of the collected blood sample.

Syringe-like apparatus with removable capillary cartridge

The syringe of the present invention includes a tubular body having a plunger slidably received therein in fluid tight relationship so as to define a void space at the leading end of the syringe when the plunger is fully inserted, the void space being in communication with (1) a connector adapted to receive a hypodermic needle or the like and (2) a vent opening laterally through the side wall of the tubular body. The vent has a conduit connected thereto so that the initial flow of blood into the syringe will pass through the void space and into the conduit to purge air from the void space so that the subsequent flow of blood into the syringe will be free of air contamination. In the preferred form of the syringe, the conduit is connected to a second tubular body having a plunger therein adapted to create a low pressure zone to draw blood from the artery of a patient whose blood pressure is not sufficient to pump blood naturally into the syringe.

Syringe for taking blood samples

A syringe for taking blood samples includes a tubular body having a main plunger slidably received therein in fluid tight relationship. The tubular body has an opening through the leading end in communication with connection means for receiving a hypodermic needle or the like. The main plunger has a passage there-through in communication with the opening in the leading end of the tubular body and an auxiliary plunger is slidably received in said passage to assist in initially drawing blood into said passage to purge gaseous materials from the opening in the leading end of the tubular body before blood is allowed to flow into the internal chamber of the tubular body.

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Thornton, CO, United States of America

Donald L Bailey