Abbott Laboratories Corporation

Abbott Cardiovascular Systems, Inc.

Oxford Biomedical Research, Inc.

Lumoptik, Inc.

Donald J Verlee

Keith R Cromack

Peter J Tarcha

John C Tanner, Ii

John S Norman

Peter J Karas

John K Moore

Steven P Hellstrom

Richard F Daubert, Jr

Richard Quint

John L Toner

Sandra E Burke

Sanjay Shrivastava

Anton G Clifford

Donald J Hayes

David B Wallace

Ho-Wah Hui

John L Vcelka

Denis Marc Callewaert

Robert W Jaekel

Charles Jack Fisher

Enrique Martinez

Kenneth R Houseman

Thomas Janicki

Ho-Wa Hui

Systems and methods to assist a practitioner to confirm location of a distal tip of a needle within a patient include confirming tactile feedback from a needle insertion to a point of loss of resistance of fluid flow and by viewing a display showing color of a tissue plane at the distal tip of the needle at the point of loss of resistance.

Light assisted needle placement system and method

An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The interventional device has a controlled local areal density of beneficial agent for systemic delivery or delivery to the luminal wall. The local areal density of beneficial agent may be varied along the prosthesis. The interventional device includes overlapping or bifurcated stents having a controlled areal density of beneficial agent.

Prosthesis having varied concentration of beneficial agent

A method for securing an implantable medical device onto a balloon which includes applying a coating, which includes a film-forming polymer and at least one solvent, to the outer surface of the balloon. The solvents can include alcohol, water, ether and combinations thereof. The film-forming polymer can include a zwitterionic polymer, such as, for example a phosphorylcholine polymer. The coating can be applied to the entire balloon surface or a portion of the surface. The implantable medical device is then positioned on the outer surface of the balloon and secured. The film-forming polymer is then allowed to cure in order to define an adhesive layer between an inner surface of the implantable medical device and the outer surface of the balloon. This method prevents or reduces the leaching or redistribution of any therapeutic agents dispersed within or on the surface of the implantable medical device.

Method of securing a medical device onto a balloon and system thereof

A method for detecting the presence of an aldehyde in a sample comprises steps of exposing the sample at room temperature to a test medium to catalyze the formation of optically detectable quantities of a product within a time period of no more than 60 minutes and without applying any external heat to the sample or test medium, the test medium comprising a indicator that is a nucleophilic compound having acidic protons at the nucleophilic center and at least one acid, and measuring the optical changes that occur as a result of the catalysis.

Method and apparatus for the identification of aldehydes

A method of making a medical device which is at least partially bio-erodible and which exhibits controlled elution of therapeutic agent.

Method of integrating therapeutic agent into a bioerodible medical device

A medical device which is at least partially bio-erodible and which exhibits controlled elution of therapeutic agent.

Integration of therapeutic agent into a bioerodible medical device

An interventional device for delivery of beneficial agent to a lumen and methods of loading and manufacture of the same, which include a prosthesis loaded with beneficial agent to provide a controlled dosage concentration of beneficial agent to the lumen. The beneficial agent is loaded onto the prosthesis by a fluid-dispenser having a dispensing element capable of dispensing the beneficial agent in discrete droplets, each droplet having a controlled trajectory. The method of loading beneficial agent includes dispensing beneficial agent in a raster format and/or an off-axis format along a dispensing path.

System and method of loading and detecting beneficial agent on a prosthesis

Method of loading beneficial agent to a prosthesis by fluid-jet application

System of loading beneficial agent to a prosthesis by fluid-jet

A cap assembly for a container has a hollow housing with an upper end that receives a fluid transfer device and a lower end that engages a stopper on the container. The housing has an internal cavity open at the upper and lower ends and a radially outwardly extending portion at the lower end. A penetrator is received in the internal cavity. The penetrator has a pointed distal end opposite the stopper and an upper end constructed to be engaged by a fluid transfer device. A cap is constructed the hollow housing. The cap has a closed upper end, an open lower end, a radially outwardly extending portion at the open end, and a circumferential line of weakness connecting the upper and lower ends. A ferrule is over the radially outwardly extending portion of the hollow housing and the radially outwardly extending portion of the cap.

Container cap assembly having an enclosed penetrator

A penetrator for penetrating a stopper sealing an opening in a container. The penetrator includes a stamped piece of sheet material formed to define a shank having a length. A groove extends along the length of the shank. The shank has a pointed distal. The stamped piece of sheet material further includes a bearing plate extending from the shank at a proximal end opposite the distal end of the shank.

Penetrator for a container occluded by a stopper

A cap assembly is provided for mounting over the mouth of a container which is occluded with a stopper. The cap assembly includes a housing, a moveable piercing member or penetrator within the housing, a removable overcap over the housing, and a ferrule connecting the housing to the container. A preferred form of the penetrator is fabricated from sheet metal in a progressive die stamping process. One form of the overcap includes a frangible construction that permits the upper part of the overcap to be torn away to expose the upper portion of the housing.

A closure is provided for mounting across the mouth of a container and through which liquid can be withdrawn with a fluid transfer device having a male member. The closure includes a body for being disposed on the container across the container mouth. The body defines a passage with an exterior opening for matingly receiving the male member of the fluid transfer device. A frangible seal initially extends across the passage in the body to occlude the passage. The seal is broken when it is engaged by the male member of the fluid transfer device, thereby establishing fluid communication between the fluid transfer device and the interior of the container.

Growing community of inventors

Libertyville, IL, United States of America

Donald J Verlee