Cornell Research Foundation Inc.

Riverside Research Institute

Donald J Coleman

Ronald H Silverman

Dan Z Reinstein

Frederic Louis Lizzi

David Najafi

George Simoni

Apparatus is provided for high frequency ultrasound examination of the anterior segment of a patient's eyes. A liquid bath is established about a first eye of the patient to be examined. A fixed ultrasound transducer is placed in contact with the liquid bath and directs the beam of ultrasound energy to the first eye and receives echoes of the ultrasound energy. A fixation source is juxtaposed to the second eye of the patient and displays a fixation target. A controller operates the fixation source to move the fixation target relative to the second eye, while the patient moves the second eye so as to remain focused on the fixation target. The movement of the second eye causes the first eye to move concurrently and enables relative movement between the beam of ultrasound energy and anterior segments of the first eye, while maintaining near orthogonality between the ultrasound beam and the surface of the eye. By tracking the position of the second eye, the position of the first eye, and hence of each pulse/echo sequence, is ascertained, enabling image construction and biometric determinations of the anterior segment anatomy to be performed.

Ultrasonic scanning of the eye using a stationary transducer

An apparatus for assuring vertical alignment of visual axes of a patient's eyes includes an eye cup that enables establishment of a liquid bath in which a surface of a cornea of a supine patient's first eye is completely submerged. A first light source is positioned above the liquid bath and directs a beam of alignment light to the submerged eye. A second light source is positioned above the patient's second eye and directs a beam of adjustment light to its corneal surface. Apparatus is provided that enables relative movement between the first and second light sources so as to enable the light sources to be moved into a position where the patient indicates a fusion of the light sources into a single spot, at which point it is known that the visual axis are vertical and aligned. The liquid bath assures that the beam of alignment light from the first light source is only in focus at the patient's eye when the first light source is directly coincident with the vertical axis of the first eye. Any deviation from that vertical axis results in blurring of the image due to refractive effects within the liquid bath.

System and method for producing and maintaining parallel and vertical

An ultrasonic biometer images an eye structure and enables measurement of a cornea's thickness at various points about the cornea's surface curvature. The biometer employs a liquid bath in contact with the corneal surface and includes a curved track positioned above the liquid bath, the curved track having a path that closely approximates the surface curvature of the corneal surface. An ultrasonic transducer (having a central axis) is movably mounted by a connector structure along the track and is positioned in communication with the liquid bath. The connector structure operates to maintain the central axis of the ultrasonic transducer perpendicular to a tangent drawn to the curved track, at a plurality of locations along the track. When the connector structure is moved along the curved track, it enables an ultrasonic beam, generated by the transducer, to interrogate areas of the corneal surface, with the angle of incidence of the beam being substantially orthogonal to the surface.

Ultrasound system for corneal biometry

An ultrasound system that enables determination of layer thicknesses and contours of a multi-layer organic body includes a transmitter/receiver for obtaining a radio frequency signal from echoes over a plurality of points on the organic surface. Each radio frequency signal is then deconvolved to remove apparatus generated noise and filtered to create an analytic signal that exhibits a magnitude related to an instantaneous rate of arrival of total echo energy received by the transmitter/receiver. Analytic signals from adjacent parallel scans are then cross-correlated and magnitude detected to determine energy peaks to enable accurate determination of echo producing surfaces of each layer of the multi-layer organic body across the plurality of interrogation points. In the application of the invention to Corneal Epithelium Mapping, a pupil monitoring system is included that disables the measurement system if the pupil's gaze wanders so as to cause a diversion of the optical axis.

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Haworth, NJ, United States of America

Donald J Coleman