Purdue Pharma L.p.

Accencio LLC

Don Kyle

Kevin Brown

Kevin Brogle

Paul Blake

Laykea Tafesse

Chiyou Ni

Minnie Park

A system and method for extrapolating a set of specific representational identifiers that are represented or covered by a generic representational identifier found in a target document. Queries are constructed and performed on a corpus of source documents in which members of the extrapolated set of specific representational identifiers are compared to a database of representational data. By matching representational data in this way, any overlap between the generic representational data and specific instances of the generic representational identifier within the source documents is determined. In a more specific implementation, the system and method reduces the scope of the generic representational identifier such that the reduced scope generic representational identifier encompasses only novel specific representational identifiers.

Chemical formula extrapolation and query building to identify source documents referencing relevant chemical formula moieties

The invention relates to substituted pyridine compounds of Formula I: (I) or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein A, X, A, R, R, R, G, and z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula I to treat a disorder responsive to the blockade of sodium channels. Compounds of the present invention are especially useful for treating pain. 

Pyridine compounds as sodium channel blockers

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Yardley, PA, United States of America

Don Kyle