Centre National De La Recherche Scientifique

Institut Mines-telecom

Ecole Des Mines De Nantes

L'air Liquide, Soci&#xe9;t&#xe9; Anonyme Pour L'etude Et L'exploitation Des Proc&#xe9;d&#xe9;s Georges Claude

Universite Claude Bernard – Lyon1

Université De Nantes

Université Clermont Auvergne

Nantes Université

Association Pour La Recherche Et Le Developpement Des Methodes Et Processus Industriels

Dominique Thers

Fabien Durand

Pierre Briend

Jérôme Donnard

Jean-Pierre Cussonneau

Patrick Le Ray

Eric Morteau

Noël Servagent

Jean-Sébastien Stutzmann

Romain Berny

Hervé Carduner

Richard Vandaele

Hervé Chanal

Hervé Mathez

Mokrane Dahoumane

Olivier Lemaire

Lucia Gallego Manzano

Mounir Abaline

Samuel Manen

Nicolas Pillet

Elena Aprile

Wan-Ting Chen

A method for monitoring a hadron beam during hadron-therapy treatment of a subject including tumour cells labelled with a radiopharmaceutical product, in which the hadron beam includes a plurality of discrete hadron bursts, the method including the following steps: when a burst impacts on the subject, detecting the prompt gamma generated by the interaction of the hadrons of the burst with the tissues of the subject using a Compton telescope and reconstructing an image of the interaction volume; when no burst impacts on the subject, extracting the position of the tumour cells labelled with the radiopharmaceutical product using the Compton telescope and reconstructing an image of the total volume of the tumour; comparing the image of the interaction volume and the image of the total volume of the tumour so as to locate the measured interaction volume relative to the measured total volume of the tumour.

Method and system for monitoring a hadron beam during hadron-therapy treatment of a subject

The present disclosure relates to a method for locating a radionuclide emitting positons and having a child core emitting a photon by de-excitation, that includes detecting a radionuclide response line using a positon-emitting tomography camera. According to the disclosure, for each of the arrangements ordered by pairs of first and second interactions of the Compton type detected by a Compton telescope, the method comprises determining the angle between the direction of the incident photon of the first interaction and the geometrical axis connecting the position of the first interaction with the position of the second interaction, determining the half-aperture cones of the angle in which the geometrical surface does not include an intersection with line, selecting at least one cone in which the geometrical surface includes an intersection with line, selecting the radionuclide position from said reconstructed intersection of the response line with the geometrical surface of the selected cone.

Process for locating a positron radionuclide, applications and device for implementing same

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Treillières, France

Dominique Thers