Centre De Cooperation Internationale En Recherche Agronomique Pour Le Developpement (cirad)

Centre National De La Recherche Scientifique

Centre De Cooperation Internationale En Recherche Agronomique Pour Le Developpement

Dominique Martinez

Roger Frutos

Conception Ferraz

Nathalie Vachiery

Jacques Demaille

Jonathan Gordon

Damien Meyer

Thierry Lefrancois

Embodiments of the present disclosure relate to a vaccine composition comprising a bacterial strain with a deleted or inactive ntrX gene.

Live attenuated bacterial strain and its use as a vaccine

The invention provides a combination of target genes that are useful as genetic markers for the strain-specific detection of. The invention also provides diagnostic methods using said combination of markers.

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The invention provides genes that are unique either tostrain Gardel or tostrain Welgevonden, or allelic couples which are present in both strains but whose sequences differ between the two strains, as genetic markers to differentiate between these two strains. The invention also provides diagnostic methods using these genetic markers.

Growing community of inventors

Sauve, France

Dominique Martinez