Ethypharm, Inc.

Dominique Marechal

Philippe Chenevier

Phillippe Chenevier

Yu-zhang Hu

Amina Faham

Wei-hong Yang

Wei-Hong Yang

Yu-Zhang Hu

The invention relates to a directly-compressible gastro-resistant spheroid. The spheroid comprises: (i) a core containing one or more active substances; (ii) a flexible, deformable film which directly coats the aforementioned core and which comprises an enteric polymer and a mixture of saturated and/or unsaturated polyglycosylated glycerides, the fatty acids of which include at least 8 carbon atoms; and (iii) an outer water-dispersible layer containing at least one disintegrating agent. The invention further relates to multiparticular tablets comprising said spheroids.

Spheroids and multiparticulate tablets comprising them

The present invention relates to a coated particle of active substance comprising a core, said core comprising the active substance and an acidic compound, said core being coated with a taste masking coating based on a polymer which is soluble at pH of 5 or less, and which is permeable at pH above 5.

Taste-masking coated particles, process for the preparation thereof and orodispersible tablets containing said coated particles

Active principle-based coated particle, in which both the core and the coating contain active principle, includes a core which contains a first active principle while the coating contains a second active principle, which is different in nature.

Composition comprising a mixture of active principles, and method of preparation

The invention concerns coated particles with prolonged release, a method for preparing same and multiparticulate tablets comprising said coated particles.

Coated particles with prolonged release and tablets containing same

The subject of the present invention is a new stable herbal drug formulation in the form of sustained-release microgranules containingextract as well as the process for preparing it.

Sustained-release microgranules containing gingko biloba extract and the process for manufacturing these

The present invention concerns orodispersible tablets, which are able to disintegrate in the buccal cavity upon contact with saliva by formation of an easy-to-swallow suspension, in less than 60 seconds, preferably in less than 40 seconds, containing fexofenadine in the form of coated granules, and a mixture of excipients comprising at least one disintegrating agent, a soluble diluent agent, a lubricant and optionally a swelling agent, a permeabilizing agent, sweeteners, flavoring agents and colors; the process for obtaining such orodispersible tablets and the coated granules incorporated therein and the use of said orodispersible tablets in the treatment of seasonal allergic rhinitis.

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Laval, Canada

Dominique Marechal