Syngenta Crop Protection, Inc.

Syngenta Participations Ag

Syngenta Corporation

Dominik Faber

Martin Zeller

Clemens Lamberth

Martin Charles Bowden

Gottfried Seifert

Thomas Rapold

Beat Jau

Fanny Giordano

Thomas Vettiger

Alan James Robinson

Marco Passafaro

George Robert Hodges

Miroslav Terinek

Juerg Wiss

Rémy Gressly

Thomas Aitcheson Clark

Hans-Dieter Schneider

Andrew Charles Shaw

Stefan Koenig

Olivier Desponds

Fanny Delphine Brigtte Giordano

The invention relates to a process for the preparation of formula (I) which process comprises pyrolyzing a compound of formula (II) wherein X is chloro or bromo, and to compounds which may be used as intermediates for the manufacture of the compound of formula I and to the preparation of said intermediates. 

Process for the preparation of dichlorofulvene

The invention relates to a process for the preparation of 3-difluoromethyl-1-methyl-1H-pyrazole-4-carboxylic acid (9-dichloromethylene-1,2,3,4-tetrahydro-1,4-methano-naphthalen-5-yl)-amide by acylating the oxime oxygen of the compound of formula (VIII), in the presence of a solvent and an acylating agent of formula (XI) RC(X)&#x2014;CI (XI); wherein X is oxygen or sulfur; Ris chloro if X is oxygen or sulfur; or R1 is C-Calkoxy, CH&#x2014;C(&#x2550;CH)&#x2014;O&#x2014;, phenoxy or trichloromethoxy if X is oxygen; and a) if Ris chloro and the compound of formula (XI) was added to the compound of formula (VIII); reacting the so obtained product of formula (XIIa) wherein X is oxygen or sulfur; with the compound of formula (IX) b) if Ris chloro and the compound of formula (VIII) was added to the compound of formula (XI); or Ris C-Calkoxy, CH&#x2014;C(&#x2550;CH)&#x2014;O&#x2014;, phenoxy or trichloromethoxy if X is oxygen; reacting the so obtained product of formula (XII) wherein X is oxygen or sulfur; Ris chloro if X is oxygen or sulfur; or Ris C-Calkoxy, CH&#x2014;C(&#x2550;CH)&#x2014;O&#x2014;, phenoxy or trichloromethoxy if X is oxygen; with the compound of formula (IX). 

Process for the preparation of pyrazole carboxylic acid amides

A process for the preparation of a compound of formula (I), the process comprising: (i) the reaction of a compound of formula (III), with a compound of formula (IV) to give a compound of formula (II), and (ii) the reaction of the compound of formula (II) with a leaving group, to give the compound of formula (I).

Process for the synthesis of mandipropamid and derivatives thereof

The invention concerns a novel process for the preparation of 2-phenyl-2-hydroxy-N-[2-(3-alkoxy-4-hydroxyphenyl)-ethyl]-acetamides of the formula (I), wherein Ris alkyl, Rand Rare each independently hydrogen or alkyl, and Ris optionally substituted aryl or optionally substituted heteroaryl, which process comprises reacting a 2-(3-alkoxy-4-hydroxyphenyl)-ethylamine of the formula (II), wherein RRand Rare as defined above with a &#x3b1;-hydoxycarboxylic acid ester of the formula (III) or a dioxolanone of the formula (III)a, wherein Ris as defined above, and R, Rand Rindependently of each other are lower alkyl. The compounds of formula (I) are important intermediates for a novel group of fungicides derived from mandelic acid amides. 

Process for the preparation of alpha hydroxycarboxylic acid amides

A process for the preparation of a compound of formula (I) wherein Q is CH or N; Y is NOor CN; Z is CHR, O, NRor S; Rand Rare C-Calkyl or together form an alkylene bridge having two or three carbon atoms; by reacting a compound of formula HC=C(X)CHNCS wherein X is a leaving group, with a chlorinating agent in the presence of a catalytic amount of SO. to form a compound of formula (III) and the compound of formula (III) is reacted with a compound of formula RNHC(=QY)ZRwherein R, R, Y, Z and Q are as defined for compound (I).

Catalytic process for the preparation of thiazole derivatives

Growing community of inventors

Muenchwilen, Switzerland

Dominik Faber