Tissue Regeneration Therapeutics Inc.

Other

Baksh, Dolores

Davies, John E.

Zandstra, Peter

Ennis, Jane

Gomez-aristiz-abal, Alejandro

Sarugaser, Rahul

Hosseini, Morris

Lickorish, Antony David Sutton

Gomez-artistizabal, Alejandro

Dolores Baksh

John Edward Davies

Rahul Sarugaser

Antony D S Lickorish

Morris Hosseini

Jane Ennis

Alejandro Gomez-Aristiz-Abal

Peter Zandstra

John E Davies

Antony David Lickorish

Alejandro Gomez-Artistizabal

Antony David Sutton Lickorish

Described is a method of expanding human progenitor cells by suspension culturing under non-static conditions. The culturing method provides a three-dimensional space for the rapid expansion of desirable progenitors. By this method, a new compartment of multipotential progenitor cells has been identified, which give rise under differentiation conditions to progeny including osteoblasts, chondrocytes, myoblasts, adipocytes, and other non-hematopoietic cell types. Their use in cell and tissue-based engineering is described.

Progenitor cell populations, expansion thereof, and growth of non-hematopoietic cell types and tissues therefrom

Human progenitor cells are extracted from perivascular tissue of human umbilical cord. The progenitor cell population proliferates rapidly, and harbors osteogenic progenitor cells and MHC&#x2212;/&#x2212; progenitor cells, and is useful to grow and repair human tissues including bone.

Progenitor cells from wharton'S jelly of human umbilical cord

Progenitor cells from Wharton's jelly of human umbilical cord

Described herein is a method for modulating an immune reaction between lymphocytes and a body recognized by the lymphocytes as foreign. The method exploits the immunomodulating activity of a new class of progenitor cells termed HUCPVCs derived from the perivascular region of human umbilical cord. The method can also emply soluble factors exuded by cultured HUCPVCs. The method is useful to treat immune disorders including graft versus host disease, autoimmune disorders, and the like.

Immune privileged and modulatory progenitor cells

Progenitor cells from wharton's jelly of human umbilical cord

Described herein is a method for modulating an immune reaction between lymphocytes and a body recognized by the lymphocytes as foreign. The method exploits the immunomodulating activity of a new class of progenitor cells termed HUCPVCs derived from the perivascular region of human umbilical cord. The method can also employ soluble factors exuded by cultured HUCPVCs. The method is useful to treat immune disorders including graft versus host disease, autoimmune disorders, and the like.

Human progenitor cells are extracted from perivascular tissue of human umbilical cord. The progenitor cell population proliferates rapidly, and harbours osteogenic progenitor cells and MHC&#x2212;/&#x2212; progenitor cells, and is useful to grow and repair human tissues including bone.

Growing community of inventors

Mississauga, Canada

Dolores Baksh