Korea Institute of Industrial Technology

Korea Advanced Institute of Science and Technology

Korea Research Institute of Standards and Science

Dohoon Lee

Jaewon Jeong

Jin Ku Cho

Sangyong Kim

Bora Kim

Tae Geol Lee

Young-Pil Kim

Dae Won Moon

Hak-Sung Kim

Baek-Jin Kim

Eunkeu Oh

Mi-Young Hong

Seunghan Shin

Provided herein is a method for producing 5-hydroxymethyl-2-furfural (HMF) from maize syrup containing fructose including a conversion step in which a reaction product containing the 5-hydroxymethyl-2-furfural is produced by mixing and heating the maize syrup, a dioxane solvent and a solid acid catalyst, thus providing an advantage that the solvent can be easily isolated and the isolated solvent can be reused because dioxane is used as the solvent, and an advantage that the catalyst can be easily isolated and the isolated catalyst can be easily reused because a nonuniform solid acid catalyst is used.

Method for producing 5-hydroxymethyl-2-furfural from maize syrup containing fructose

The present invention relates to a metal catalyst composition for producing furfural derivatives from raw materials of lignocellulosic biomass, and method for producing furfural derivatives using the composition. The present invention comprises ruthenium chloride (RuCl) and chromium chloride (CrCl). The chromium chloride (CCl) is from 300 to 500 parts by weight on the basis of 100 parts by weight of the ruthenium chloride (RuCl). Unlike conventional furfural derivatives producing process that should go through multi step processes such as pre-process, saccharification process, etc, the present invention has an advantage of producing furfural derivatives from lignocellulosic raw material only through simple reaction process in one reaction apparatus by mixing various kinds of metal catalyst at an optimum ratio.

Metal catalyst composition for producing furfural derivatives from raw materials of lignocellulosic biomass, and method for producing furfural derivatives using the composition

Disclosed herein is a gold nanoparticle (AuNP)-based peptide chip prepared by forming a monolayer of AuNPs onto a self-assembled monolayer constructed on a solid support, and then immobilizing a peptide on the AuNPs. The AuNPs can effectively amplify the mass signal of the peptide, thus making it possible to measure the mass change of the peptide in a simple and accurate manner. Also, when secondary ion mass spectrometric analysis (spectrum or imaging) is performed on the AuNP-based peptide chip, the activities of enzymes and related inhibitors can be effectively quantified. The disclosed invention enables various enzyme activities to be analyzed rapidly and accurately, and thus can provide an important method for disease diagnosis and new drug development through the elucidation of signaling and interaction mechanisms.

Construction of gold nanoparticle-based peptide chip, and assaying enzyme activity and inhibitor effect using secondary ion mass spectrometric analysis thereof

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Seoul, South Korea

Dohoon Lee