Genofocus, Inc.

Other

Do Young Yum

Jeong Hyun Kim

Eui Joong Kim

Jae Gu Pan

Ji Eun Kang

Taek Ho Yang

Soo Young Park

Hyun Do Kim

The present invention relates to a pharmaceutical composition for preventing or treating inflammatory disease, which contains, as an active ingredient, aGF423 strain, a superoxide dismutase high-producingGF424 mutant strain, a superoxide dismutase (SOD) derived from one of these strains, or both the strain and the SOD. The superoxide dismutase derived from theGF423 strain (KCTC 13222BP), which is the active ingredient of the present invention, effectively suppresses or degrades reactive oxygen species, and thus has the effect of fundamentally preventing the causes of inflammatory bowel disease caused by reactive oxygen species. Therefore, the composition of the present invention may be developed into various products, including excellent drugs and health functional foods for preventing or treating inflammatory bowel disease.

Pharmaceutical composition for treating inflammatory bowel disease

The present invention relates to astrain that produces superoxide dismutase (SOD), and also relates to an antioxidant, anti-inflammatory pharmaceutical composition and a pharmaceutical composition and food composition for preventing or treating hyperlipidemia, which include a superoxide dismutase produced by thestrain. The compositions of the present invention exhibit excellent effects without causing side effects, and may thus be used as functional raw materials or products having an enhanced activity of preventing or treating inflammation, cancer or hyperlipidemia in the pharmaceutical drug, food, cosmetic and livestock fields.

GF423 strain, and composition for providing antioxidant and anti-inflammatory activities or preventing or treating hyperlipidemia, including polypeptide produced by the same

There is disclosed a novel membrane-bound GADH from ATCC29267, which is useful for the production of 2KDG at high yields under the condition free of intracellular metabolism. 2KDG is converted at high yields from glucose or D-gluconate by culturing a recombinant cell, free of a ketogluconate metabolism, which harbors a recombinant plasmid containing a gene encoding the GADH.

Membrane-bound gluconate dehydrogenase, gene sequence encoding the same and production of 2-keto-D-gluconate using transformed recombinant E-coli

Growing community of inventors

Daejeon, South Korea

Do Young Yum