Optimus Drugs Private Limited

Mylan Laboratories Limited

Optimus Drugs (p) Limited

Dnyandev Ragho Rane

Srinivas Reddy Desi Reddy

Venkata Srinivasa Rao Velivela

Subba Reddy Peketi

Om Dutt Tyagi

Srinivas Rao Velivela

Vellanki Siva Ram Prasad

Tushar Kumar Srivastava

Bandi Naga Durga Rao

Subbareddy Peketi

Daggula Srinivas Reddy

The present invention relates to an improved process for the preparation of Linezolid. More specifically, the present invention relates to an improved process for preparing (S)&#x2014;N-[[3-[3-fluoro-4-[4-morpholinyl]phenyl]-2-oxo-5-oxazolidinyl]methyl] phthalimide and (S)-glycidyl phthalimide intermediates, which are used in the preparation of Linezolid.

Process for the preparation of linezolid

The present invention provides a novel process for the preparation of Canagliflozin (I) and its hydrates thereof by employing novel intermediates. The present invention is also provides commercially and industrial applicable process.

Process for the preparation of Canagliflozin

An improved process is provided for the preparation of Ledipasvir and its pharmaceutically acceptable salts or solvates thereof, which is useful as an antiviral agent. This disclosure also provides a process for the preparation of key intermediates of Ledipasvir.

Process for the preparation of Ledipasvir

The present invention relates to an improved process for the preparation of Apixaban and its intermediates.

Process for the preparation of Apixaban

The present invention relates to an improved process for the preparation of Ivacaftor intermediates. The present invention is also provides industrial applicable, commercially and eco-friendly viable process for the preparation of Ivacaftor.

Industrial process for making an Ivacaftor and its intermediates

Present invention relates to an improved process for the preparation of Zopiclone and its enantiomerically enriched isomer (Eszopiclone). 6-(5-Chloropyridin-2-yl)-5-hydroxy-7-oxo-5,6-dihydropyrrolo[3,4-b]pyrazine is reacted with 1-chloro-carbonyl-4-methylpiperazine in the presence of alkali earth metal carbonates, hydroxides or oxides in a solvent medium to give Zopiclone. It is reacted with optically active acid in a mixture of water and water miscible organic solvent followed by work up to give Eszopiclone. The present invention also relates to process for the conversion of (R) or (S) Zopiclone to 6-(5-chloropyrid-2-yl)-5-hydroxy-7-oxo-5,6-dihydro-pyrrolo-[3,4-b]-pyrazine of the intermediate which can be converted to racemic Zopiclone.

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Hyderabad Telangana, India

Dnyandev Ragho Rane