New York University

Albert-ludwigs-universitat Freiburg

University of Antwerp

Dmitry Novikov

Els Fieremans

Jelle Veraart

Valerij Kiselev

Marco Reisert

Gregory Lemberskiy

Daniel K Sodickson

Jens Jensen

Joseph Helpern

Leeor Alon

Steven Baete

Jerian Jahani

Ileana Jelescu

Valeriji G Kiselev

An exemplary system, method and computer-accessible medium for generating a denoised magnetic resonance (MR) image(s) of a portion(s) of a patient(s) can be provided, which can include, for example, generating a plurality of MR images of the portion(s), where a number of the MR images can be based on a number of MR coils in a MR apparatus used to generate the MR images, generating MR imaging information by denoising a first one of the MR images based on another one of the MR images, and generating the denoised MR image(s) based on the MR imaging information. The number of the MR coils can be a subset of a total number of the MR coils in the MR apparatus. The number of the MR coils can be a total number of the MR coils in the MR apparatus. The MR information can be generated by denoising each of the MR images based on the other one of the MR images.

System, method and computer-accessible medium for facilitating noise removal in magnetic resonance imaging

An exemplary system, method and computer-accessible medium for characterizing a microstructure of a prostate of a patient can be provided, which can include, for example, generating a magnetic resonance (MR) radiofrequency (RF) pulse(s) by varying (i) a diffusion time, (ii) a diffusion gradient direction, (iii) a diffusion gradient pulse width, or (iv) a diffusion gradient pulse shape, applying the MR RF pulse(s) to the prostate of the patient, receiving a resultant MR signal from the prostate of the patient that can be based on the MR RF pulse(s), determining information regarding a plurality of compartments for the prostate from the resultant MR signal by varying an echo time or a mixing time, and characterizing the microstructure for each of the compartments by applying a microstructural model(s) to each of the compartments.

System, method and computer-accessible medium for characterizing prostate microstructure using water diffusion and nuclear magnetic resonance relaxation

An exemplary system, method and computer-accessible medium for determining an arterial input function (AIF) of a mammal(s) can be provided, which can include, for example, receiving information related to a global circulatory system of the mammal(s), and determining the AIF based on the information by modeling a blood flow in the global circulatory system of the mammal(s) in terms of an input response function(s). The input response function(s) can include a delayed input response function(s). In certain exemplary embodiments of the present disclosure, the input response function(s) can include at least three input response functions, and each of the input response functions can be from a different part of a body of the mammal(s). The AIF can be determined by coupling the input response functions. The AIF can be further determined based on a total tracer amount in an organ(s) of the mammal(s).

Computer-accessible medium for determining arterial input function

An exemplary system, method and computer-accessible medium for removing noise and Gibbs ringing from a magnetic resonance ('MR') image(s), can be provided, which can include, for example, receiving information related to the MR image(s), receiving information related to the MR image(s), and removing the Gibbs ringing from the information by extrapolating data in a k-space from the MR image(s) beyond an edge(s) of a measured portion of the k-space. The data can be extrapolated by formatting the data as a regularized minimization problem(s). A first weighted term of the regularized minimization problem(s) can preserve a fidelity of the extrapolated data, and a second weighted term of the regularized minimization problem(s) can be a penalty term that can be based a norm(s) of the MR image(s), which can be presumed to be sparse.

System, method and computer accessible medium for noise estimation, noise removal and Gibbs ringing removal

Exemplary systems, methods, and computer-accessible mediums can be provided that can generate resultant data regarding fiber tract(s) and anatomical structure(s). For example, first information related to imaging data of the anatomical structure(s) can be received. Second information related to a predictive model of further fiber tract(s) can be received. The resultant data can be generated based on the first information, the second information and a fiber cost procedure.

System, method and computer-accessible medium for obtaining and/or determining mesoscopic structure and orientation with fiber tracking

An exemplary system, method and computer-accessible medium for determining a plurality of tissue parameters of a tissue(s), can include, for example, receiving information related to a plurality of rotational invariants contained within a diffusion magnetic resonance (dMR) image(s) of the tissue(s), and generating the tissue parameters using a set of rotational invariants related to the plurality of tissue parameters using such information. The tissue parameters can be generated by factorizing a response of an individual fiber segment of the tissue(s) based on the set of rotational invariants. The response of the individual fiber segments can be factorized from an orientational distribution function ('ODF'). The individual fiber segments can be factorized using a scalar tensor factorization(s) of the rotational invariants. The set of rotational invariants can be of a rotation group SO(3).

System, method and computer-accessible medium for determining brain microstructure parameters from diffusion magnetic resonance imaging signal's rotational invariants

Method, system and computer-accessible medium for determining at least one of axonal loss or myelin degradation can be provided. For example, it is possible to receive data based on at least one of a measure of diffusion of an axonal structure or a measure of a density of axons, and determine axonal loss and/or myelin degradation based on the data. The determination can be based on axonal geometry of at least one parallel tube.

System, method and computer accessible mediums for determining neurodegeneration

Exemplary system, method, and computer-accessible medium can be provided for determining at least one property (e.g., an electrical property or a cross-section property) of at least one target. For example, it is possible to determine electromagnetic-field-related quantities associated with signals provided from the target(s). The electromagnetic-field-related quantities can be provided to procedures to relate the electromagnetic-field-related quantities to a plurality of unknown electrical property values and residual field-related unknown values of the target(s). The property(ies) of the target(s) can be determined by determining the plurality of unknown electrical property values and residual field-related unknown values of the target(s).

System, method and computer-accessible medium for providing generalized local maxwell tomography for mapping of electrical property gradients and tensors

Exemplary embodiments of a methodology, procedure, system, method and computer-accessible medium can be provided to obtain particular information relating to at least one transport property of a material containing at least one membrane, and to determine, e.g., a permeability of the membrane of the material and/or a surface area of the membrane of the material, as a function of, e.g., the obtained particular information.

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New York, NY, United States of America

Dmitry Novikov