Ajinomoto Co., Ltd.

Ajinomoto., Inc.

Dmitriy Vladimirovich Filippov

Mikhail Markovich Gusyatiner

Elvira Borisovna Voroshilova

Aleksandra Yurievna Skorokhodova

Konstantin Vyacheslavovich Rybak

Tatyana Viktorovna Leonova

Mika Moriya

Vera Georgievna Doroshenko

Yuri Nagai

Keiko Noguchi

Vitaly Grigorievich Paraskevov

Marina Evgenievna Sheremeteva

The present invention provides a method for producing L-amino acids, such as L-arginine, L-citrulline, and L-lysine, using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genusor, which has been modified to attenuate expression of one or more genes, such as the pepA, pepB, and pepD genes.

Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family, having attenuated expression of gene(s) encoding peptidase

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genusor, which has been modified to attenuate expression of the rcsA gene.

[object Object]

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genusorwhich has been modified to attenuate expression of the sfmACDFH-fimZ cluster and/or the fimZ gene.

Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of the sfmACDFH-fimZ cluster or the fimZ gene

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genusor, which has been modified to attenuate expression of one or more of the cynT, cynS, cynX and/or cynR genes.

Method for producing an L-amino acid using a bacterium of the enterobacteriaceae family with attenuated expression of any of the cynT, cynS, cynX or cynR gene or combination thereof

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genusor, which has been modified to attenuate expression of the kefB gene.

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging the genusor, wherein said bacterium has attenuated expression of a gene encoding a toxin of a bacterial toxin-antitoxin pair.

The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to genusor, which has been modified to attenuate expression of the rspAB operon.

Growing community of inventors

Moscow, Russia

Dmitriy Vladimirovich Filippov