Torrey Pines Institute for Molecular Studies

Auburn University

Florida Atlantic University

Nova Southeastern University

Dmitriy Minond

Richard Allen Houghten

Marcello Angelo Giulianotti

Adel Nefzi

Gregg B Fields

Madepalli K Lakshmana

The invention provides methods for treating cancers, such as melanoma and/or metastatic melanoma, using compounds that interact with and/or inhibit cellular proteins lamin A/C, ATP-dependent RNA helicase DDX1 (DDX1), heterogeneous nuclear ribonuclear protein H1/H2 (hnRNP H2), and/or heterogeneous nuclear ribonuclear protein A2/B1 (hnRNP A2/B1). The invention additionally provides a method for identifying compounds active against melanoma cells.

Methods for treating melanoma using small molecules

Embodiments of the present disclosure provide for compositions including a compound, pharmaceutical compositions including the compound, methods of treatment of a disease or related condition (e.g., neurological disease on condition), methods of treatment using compositions or pharmaceutical compositions, and the like.

Compounds and methods of treating neurological disorders

Growing community of inventors

Fort Lauderdale, FL, United States of America

Dmitriy Minond