Max-Planck-Gesellschaft Zur F&#xf6;rderung Der Wissenschaften E. V.

Miltenyi Biotec B.v. Co., Kg

Dirk Meineke

Stefan W Hell

Christian Dose

Vladimir Belov

Erdmann Rapp

Jonathan Fauerbach

Matthias Bischoff

Gyuzel Mitronova

Elizaveta Savicheva

Laura Thomas

Kirill Kolmakov

Marvin J Boehm

René Hennig

Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis The invention relates to fluorescent dyes with multiple negatively charged groups in their ionized form which are aminoacridone sulfonamides or 1-aminopyrenes having of one of the following general formulae A-D: Formula (A), Formula (B), Formula (C), Formula (D), wherein the ionizable groups X are typically selected from the following: SH, COOH, SOH, OSOH, OP(O)(OH), OP(O)(OH)R, P(O)(OH), P(O)(OH)R, where R═C-Calkyl or substituted C-Calkyl. The invention further relates to the use of these dyes as fluorescent tags, in particular for reducing sugars and glycans.

Sulfonated 2(7)-aminoacridone and 1-aminopyrene dyes and their use as fluorescent tags, in particular for carbohydrate analysis

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Cologne, Germany

Dirk Meineke