Basf Aktiengesellschaft

Hte Aktiengesellschaft the High Throughput Experimentation Company

Basfaktiengesellschaft

Dirk Demuth

Hartmut Hibst

Stephan Andreas Schunk

Joaquim Henrique Teles

Norbert Rieber

Klaus Breuer

Wolfram Stichert

Jens Klein

Klaus Harth

Thomas Fetzer

Wolfgang Strehlau

Armin Brenner

Helmuth Menig

Wilhelm Ruppel

Alfred Hagemeyer

Michael Baier

Daniel Heineke

Heinz Etzrodt

Peter Resch

Heinz Rutter

Harro Wache

John Michael Newsam

Udo Rheude

Andreas Sundermann

Sebastian Storck

Christopher William Rieker

Ludwig Wambach

Alfred Haas

Wulf Kaiser

Torsten Zech

Dieter Hoenicke

Thomas Wendrich

Volker Pratsch

Stefan Kaeshammer

The present invention relates to a device () for analyzing and archiving at least one combinatorial library of materials, comprising at least:

Device for archiving and analyzing of materials

A process and apparatus for testing material libraries, in particular catalysts, by means of coupled use of at least two analytical methods, preferably IR thermography and mass spectrometry. Owing to the selected arrangement, the disadvantages of the two previously known individual methods are compensated for: the subsequent selectivity determination for selected sections by means of mass spectrometry invalidates the argument against IR thermography, of only being able to determine activities; the rapid integrated determination of potentially 'good' materials via IR thermography prevents an excessive loss of time by needing to test all materials of a library successively with the mass spectrometer. The reactor design permits, firstly, the integral recording of the entire reactor through a window which is transparent for the corresponding method and, secondly, permits the simultaneous, automated application of a second analytical method (for example mass spectrometry) to selected materials of a material library, which have been rated as active by the optical method. In the case described, the optical method provides information on the material activity for a set problem, and the second analytical method determines the selectivity of the materials.

Process and apparatus for the combinatorial production and testing of catalyst material libraries by using at least two analytical methods

The present invention relates to an arrangement, in particular for the parallel testing of a plurality of building blocks of a material library for performance characteristics, in which the arrangement has a block containing at least one reaction module and at least two heating/cooling modules.

Arrangement for the parallel testing of materials

The invention relates to a novel structured catalyst bed which optionally comprises at least one part bed comprising at least one catalytically active mixture of oxides of the main group metals and transition metals and additionally comprises at least one catalytically active part bed comprising at least silver, at least one alkali metal and a porous support material and finally and necessarily at least one catalytically active part bed comprising at least one alkali metal phosphate and at least one sheet silicate.

Structured catalyst bed

Olefinically unsaturated hydrocarbons are prepared from corresponding paraffinic hydrocarbons, in particular propylene is prepared from propane, by dehydrogenation over a catalyst comprising an oxide of a transition metal of group IV B of the Periodic Table, eg. TiOor ZrO, and possibly at least one element selected from among elements of transition group VIII, eg. palladium, platinum or rhodium, and/or an element of transition group VI, eg. chromium, molybdenum or tungsten, and/or rhenium and/or tin and possibly a compound of an alkali metal or alkaline earth metal, a compound of main group III or transition group III or zinc.

Preparation of olefins, particularly of propylene, by dehydrogenation

The invention relates to a method for combinatorially producing a library of materials by means of an electrochemical deposition in an array. The inventive library is made from an array of containers that consist of an electroconductive material, are open to the top and are electroconductively connected to a shared current supply device and is made from a corresponding array of auxiliary electrodes that are electroconductively connected to a shared current supply device and are arranged in such a way that an auxiliary electrode plunges into a container respectively or can be introduced therein without touching said container. The inventive method comprises the following steps: filling the containers with electrolytes having different compositions and containing electrolytically separable elements and applying an electric voltage between the current supply devices of the containers and auxiliary electrodes for obtaining an electrolytic deposition on the surfaces of the containers.

Method for producing material libraries by means of electrochemical deposition

The invention relates to a method for the automated production and iterative automated optimization of a substance library and/or at least one reaction parameter relating to a performance characteristic comprising at least two substances comprising the steps of: a) defining at least one production parameter and at least one test parameter; b) automated preparation of a substance library by producing at least two substances on the basis of the at least one production parameter; c) automated testing of the at least two substances of the substance library with respect to at least one performance characteristic on the basis of the at least one test parameter; d) evaluating the test using electronic data analysis; e) varying the at least one production parameter and/or the at least one test parameter for optimizing the performance characteristics, and single or repeated repetition of steps b) to e) or c) to e); characterized in that the steps b) to e) are carried out in an integrated automated process.

Computer-aided optimization of substance libraries

In a process for the combinatorial production of a library of materials in the form of a two-dimensional matrix in the surface region of a planar substrate by sputtering, the planar target used for the sputtering is arranged in parallel to the planar substrate and has surface regions of different chemical composition.

Production of material libraries using sputter methods

A process for preparing arrays of two or more heterogeneous catalysts, heterogeneous catalyst precursors, or combinations thereof in a body having preferably parallel through-channels. In this process, a solution, emulsion or dispersion of elements present in the catalyst, catalyst precursor, or combination thereof, is first prepared, and is used to simultaneously or successively coat the channels of the body to produce freshly impregnated moist channels. These channels are then treated and reacted with one or more reactive gases, and the coated body is optionally heated in the presence or absence of inert or reactive gases.

Combinatorial preparation and testing of heterogeneous catalysts

Olefinically unsaturated hydrocarbons are prepared from corresponding paraffinic hydrocarbons, in particular propylene is prepared from propane, by dehydrogenation over a catalyst comprising an oxide of a transition metal of group IV B of the Periodic Table, eg. TiO or ZrO , and possibly at least one element selected from among elements of transition group VIII, eg. palladium, platinum or rhodium, and/or an element of transition group VI, eg. chromium, molybdenum or tungsten, and/or rhenium and/or tin and possibly a compound of an alkali metal or alkaline earth metal, a compound of main group III or transition group III or zinc.

Method and catalyst for producing olefins, in particular propylenes, by dehydrogenation

Preparation of carbonyl compounds

Method for producing enol ethers

Unsaturated ketones of the formulae Ia and Ib

Preparation of unsaturated ketones

Method for producing carbonyl compounds

A process for preparing compounds of the formulae I and II ##STR1## where R.sup.1 and R have the meanings indicated in the specification by an addition reaction of a compound of the formula III

Addition reaction of hydroxy1-containing compounds with alkynes or

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Nussloch, Germany

Dirk Demuth