Eth Zurich

Harvard College

University of California

Universitatsspital Basel

Abb Schweiz Ag

Biotronik Ag

Dimos Poulikakos

Aldo Ferrari

Patrick Galliker

Daniele Foresti

Manish Kumar Tiwari

Tobias Lendenmann

Maximilian Fischer

Simone Bottan

Martin Grapow

Bernhard Winkler

Julian Schneider

Friedrich Eckstein

Jaewon Chung

Constantine P Grigoropoulos

Alexander Borck

Alexander Rzany

Bjoern Klocke

Jaroslav Hemrle

Jens Ulmer

Matthias Gratz

Robert Schmiedl

Vartan Kurtcuoglu

Heng Pan

Nicole Renée Bieri

Seung-Hwan Ko

Philipp Schoen

Christos Stamatopoulos

Tanmoy Maitra

Efstratios Mitridis

Thomas Schutzius

Iwan HÄCHLER

Gabriel Schnoering

Björn Klocke

Philipp Schön

The invention relates to an artificial vascular graft comprising a primary scaffold structure encompassing an inner space of the artificial vascular graft, said primary scaffold structure having an inner surface facing towards said inner space and an outer surface facing away from said inner space, a coating on said inner surface, wherein a plurality of grooves is comprised in said coating of said inner surface. The primary scaffold structure comprises further a coating on said outer surface. The primary scaffold structure and the coating on said inner surface and on said outer surface are d designed in such a way that cells, in particular progenitor cells, can migrate from the periphery of said artificial vascular graft through said outer surface of said coating, said primary scaffold structure and said inner surface to said inner space, if the artificial vascular graft is used as intended. The invention relates further to a method for providing said graft.

Artificial vascular graft

A method for solidifying a polar substance, in particular water, is presented which comprises the steps of: providing a coolable, hydrophobic, preferably super-hydrophobic, condensation surface within an interior of a container; partially filling the container with a polar substance, preferably in liquid form, and an immiscible additive, preferably in liquid form, so that the condensation surface remains at least partially unsubmerged; cooling the hydrophobic condensation surface to a temperature Tbelow a solidification temperature Tof the polar substance; and removing solidified polar substance from the container.

Method and apparatus for solidifying a polar substance

A method of printing a print pattern onto a substrate with a print head comprises a plurality of nozzles, where the print head has a rectangular active print head area which includes all of the nozzles. The active print head area is delimited by four sides defining a primary and a secondary direction. The method comprises i) decomposing the print pattern into a plurality of print pattern segments that have dimensions along the primary and secondary direction which are smaller than the dimensions of the active print head area along the primary and secondary direction; ii) assigning each print pattern segment to exactly one nozzle; iii) causing each nozzle to print the print pattern segment assigned to said nozzle. The print head is moved during printing of each print pattern segment within an area that is smaller than said active print head area.

Print pattern generation on a substrate

The present invention contains a printing apparatus and a method, e.g., for ejecting inks (i.e., pure liquids, mixtures, colloids, etc.) for a very broad range of physical properties (such as viscosity). Acoustic forcesmay be generated by an emitterand a reflectorto detach dropletsfrom a nozzle. The ink may be advanced through the nozzleby a standard back pressure system. A reflectorless chambermay enhance acoustic forcesand the dropletsmay be ejected at a bottomof said chamber, so that dropletsmay be deposited on any substrate

Acoustophoretic printing apparatus and method

A print head () for depositing a liquid on a substrate comprises a layer structure including a stop layer () made of a dielectric material, an electrically conducting device layer (), and an insulator layer () made of a dielectric material. A nozzle () is formed in the layer structure. The nozzle has a nozzle opening () for ejecting the liquid. A ring trench () is formed around the nozzle. The nozzle opening and the ring trench are radially separated by an annular nozzle wall (). An ejection channel () is formed adjacent to the ring trench along the direction of ejection. An extraction electrode () is arranged on the insulator layer () and surrounds the nozzle.

Multi-nozzle print head

A method for the self-assembled production of a topographically surface structured cellulose element. First, a mold is provided having on one side a first surface which is in a complementary manner topographically structured and which is permeable to oxygen. Next, a liquid growth medium containing cellulose producing bacteria is provided. Then, the mold is placed to form a interface such that the side of the mold with the first surface is in direct contact with the liquid growth medium, and an opposite side is facing air or a specifically provided oxygen containing gas surrounding. This allows bacteria to be produced and deposit cellulose on the first surface and developing on the interface a surface structured surface complementary thereto, until a cellulose layer with a thickness of the element of at least 0.3 mm is formed. Finally; the element is removed from the mold.

Method for the production of structured cellulose patches or elements and devices made using such a method

The present invention contains a printing apparatus and a method, e.g., for ejecting inks (i.e. pure liquids, mixtures, colloids, etc.) for a very broad range of physical properties (such as viscosity). Acoustic forcesmay be generated by an emitterand a reflectorto detach dropletsfrom a nozzle. The ink may be advanced through the nozzleby a standard back pressure system. A reflectorless chambermay enhance acoustic forcesand the dropletsmay be ejected at a bottomof said chamber, so that dropletsmay be deposited on any substrate

The present invention refers to an implant with a surface layer having a topographic modification. The topographic modification includes a line pattern with ridge and groove widths of 0.9 to 1.1 &#x3bc;m and a ridge height of more than 0.9 &#x3bc;m.

Implant with a surface layer having a topographic modification

The present invention relates to systems, materials and methods for the formation of conducting, semiconducting, and dielectric layers, structures and devices from suspensions of nanoparticles. Drop-on-demand systems are used in some embodiments to fabricate various electronic structures including conductors, capacitors, FETs. Selective laser ablation is used in some embodiments to pattern more precisely the circuit elements and to form small channel devices.

Maskless nanofabrication of electronic components

For forming a fine structure of a desired material, nanoparticles of the same material are prepared in a suspension. A layer of the suspension is applied by a drop-on-demand printing system to a substrate. At least part of the layer is exposed to laser light for melting the nanoparticles at least partially. Upon solidification, the molten particles are sintered together to form the desired structure. Due to the low melting point of nanoparticles as compared to the melting point of bulk material, this procedure avoids damage to the substrate and provides a better control over the structure generation process. It can be used for generating metallic and non-metallic structures on various substrates. The laser light may have non-Gaussian intensity distribution or can combine multiple beams of Gaussian and non-Gaussian distribution for improving the quality of the generated structure, or it may be pulsed for improved control of the heat flow into the substrate.

Method for producing a structure using nanoparticles

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Zollikon, Switzerland

Dimos Poulikakos