Ripple Therapeutics Corporation

Dimitra Louka

Ian Charles Parrag

Hans Christian Fischer

Wendy Alison Naimark

Matthew Alexander John Statham

Kyle Giovanni Battiston

Leonard Pinchuk

Roseita Esfand

Jared A Demorat

Robert William Henson

Eli B Nichols

The disclosure relates to compounds and compositions for sustained release of ocular therapeutics.

Ocular inserts comprising a covalently linked steroid dimer

Provided herein are needle assemblies for intravitreal injection of an implant into an eye of a patient through an unsheathed state and a sheathed state. Such needle assemblies are precise and accurate for proper treatment and prevent further damage to the eye.

Intravitreal injector

The disclosure features dexamethasone prodrug dimers of dexamethasone and pharmaceutical compositions thereof useful for, e.g., the extended release of a drug and for the treatment of a disease or condition.

Dexamethasone prodrug compositions and uses thereof

The disclosure features pharmaceutical compositions formed from prodrug dimers for the extended delivery of a drug and for the treatment of a disease or condition.

Glass formulations and uses thereof

Growing community of inventors

Toronto, Canada

Dimitra Louka