Daiichi Sankyo Company, Limited

Ranbaxy Laboratories, Inc.

Dilip J Upadhyay

Biswajit Das

Rita Katoch

Masao Itoh

Hiroaki Inagaki

Tetsunori Fujisawa

Saito Higuchi

Aki Yokomizo

Toshifumi Tsuda

Jasbir Singh Arora

Shahadat Ahmed

Anish Bandyopadhyay

Santosh Haribhau Kurhade

Sujata Rathy

Soma Ghosh

Abhijit Datta Khoje

Arti Gujrati

A compound represented by the following formula (I) or a salt thereof:   

Amino group-containing pyrrolidinone derivative

Provided herein are substituted aromatic compounds, which are tRNA synthetase inhibitors, and hence can be used as antimicrobial agents. Compounds described herein can be used for the treatment or prevention of a condition caused by or contributed to by gram positive, gram negative, anaerobic bacteria or fungal organisms, more particularly against bacterium, for example,or Enterobactericeae, and fungal organisms, for example,, or. Processes for the preparation of these compounds, pharmaceutical compositions thereof, and methods of treating microbial infections are also provided.

Antimicrobial agents

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Haryana, India

Dilip J Upadhyay