Janssen Pharmaceutica

Other

Dilip J Gole

R Saul Levinson

J Desmond Davies

Paul K Wilkinson

James Carbone

A fast dissolving, solid dosage form defined by a matrix containing gelatin, pectin and/or soy fiber protein and one or more amino acids having from about 2 to 12 carbon atoms is disclosed.

Pharmaceutical and other dosage forms

A method is disclosed for preparing pharmaceutical and other matrix systems that comprises solidifying a matrix composition dissolved or dispersed in a first solvent and subsequently contacting the solidified matrix with a second solvent that is substantially miscible with the first solvent at a temperature lower than the solidification point of the first solvent, the matrix components being substantially insoluble in the second solvent, whereby the first solvent is substantially removed resulting in a usable matrix.

Methods of preparing bulk delivery matrices by solid-state dissolution

Preparation of pharmaceutical and other matrix systems by solid-state

Growing community of inventors

Ann Arbor, MI, United States of America

Dilip J Gole