Symrise Ag

Symrise Gmbh & Co Kg

Dragoco Gerberding & Co. Ag

Dragoco Gerberding & Co. Gmbh

Dietmar Schatkowski

Wilhelm Pickenhagen

Michael Backes

Oskar Koch

Nadine Heinemeier

Walter Kuhn

William Johncock

Tobias Vössing

Katharina Reichelt

Ernst-Joachim Brunke

Johannes Panten

Stefan Brennecke

Stefan Lambrecht

Marcus Betzer

Burghard Wilkening

Ernst Joachim Brunke

Daniela Knoop

Willi Krieger

Karl-Georg Fahlbusch

Hartmut Struwe

Susanne Otte-Hölscher

Klaus Schafer

Martin Heinemeier

Artur Dueck

Lars Meier

Christel Jahnke

Bodo Jahnke

The present invention relates to a method for oxidizing beta-caryophyllene with oxygen, in particular atmospheric oxygen, which avoids the use of catalysts, enzymes and solvents. Furthermore, the present invention provides a mixture comprising certain caryophyllene oxides as well as their use as a flavor and/or fragrance. The present invention also relates to products and semi-finished products comprising the mixture according to the invention.

Process for preparing caryophyllene oxide

The present invention relates to, according to a primary aspect, a method for manufacturing a mixture comprising rotundone. A further aspect of the present invention relates to mixtures containing rotundone as well as their use for generating, imparting or modifying, preferably enhancing, one or several taste and/or olfactory impressions. Moreover, the invention relates to a pharmaceutical preparation for nutrition, for oral care or for pleasure or a cosmetic pharmaceutical preparation or a pharmaceutical preparation intended for oral consumption or an intermediate good for manufacturing a pharmaceutical preparation for nutrition, for oral care or for pleasure or a cosmetic pharmaceutical preparation or a pharmaceutical preparation intended for oral consumption comprising a mixture according to the invention and furthermore to a method for manufacturing said preparation or intermediate good.

Method for producing rotundone-containing mixtures

The present invention relates in particular to a mixture comprising or at least essentially consisting of compound of formula (Ia) and (beta,beta-(4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole) of the formula (Ib), wherein the weight ratio of the compound of the formula (Ia) to the compound of the formula (Ib) in the mixture is in the range from 90:10 to 99:1. The present invention further relates to a method for producing such a mixture, to new odorant and/or aroma substance compositions, and to the use of a mixture of the invention (a) for masking or diminishing the one or more unpleasant olfactory impressions of one or more unpleasantly smelling substances, and/or (b) for intensifying the one or more pleasant olfactory impressions of one or more pleasantly smelling substances.

Mixtures having (4aR,5R,7aS,9R)-octahydro-2,2,5,8,8,9a-hexamethyl-4H-4a,9-methanoazuleno(5,6-d)-1,3-dioxole)(Ambrocenide)

A method is described for producing a compound having the formula (I) or an admixture comprising a compound having the formula (I),having the following steps: where Rand Rindependently of each other signify hydrogen or a branched or unbranched alkyl group having from 1 to 12 carbon atoms andwhere R, R, R, R, R, R, R, Rand Rindependently of each other signify hydrogen, hydroxy or a branched or unbranched alkyl or alkoxy group having from 1 to 12 carbon atoms and An admixture comprising a compound of the formula (I) and other components is further described.

Method for producing indanone derivatives

Process for esterification of farnesol in an initial mixture comprising alpha-bisabolol, farnesol and optionally other components, with the following steps:

Process for removing farnesol from mixtures with alpha-bisabolol

The sensory properties of the diastereomeric enantiomer pairs and of the pure enantiomers of the compound 2-methyl-4-phenyl-1,3-dioxolane are described. The cis compounds (2R,4S)-2-methyl-4-phenyl-1,3-dioxolane and (2S,4R)-2-methyl-4-phenyl-1,3-dioxolane are the most sensorially valuable. These enantiomers and mixtures thereof are particularly suitable for use as a sensorially active substance, for example as a fragrance.

2-methyl-4-phenyl-1,3-dioxolane

A method is described for the preparation of a trimethylcyclohexyl-alkan-3-ol containing a proportion of trans isomer of Formula Dwhere

Method for the preparation of trimethylcyclohexyl-alkan-3-ols containing a high proportion of trans isomers

Isolongifolenyl ethers, their preparation and their use

Cyclic cedrene acetals of the general formula A are described, in which the wavy lines represent the .alpha.- and .beta.-configurations, and R and R.sub.1 are the radicals below: ##STR1## R=R.sub.1 =H R=H, R.sub.1 =Me/R=Me, R.sub.1 =H

Cyclic cedrene acetals, their preparation and their use

An improved process for production of an isomer mixture of Z- and E-2-�2-Methyl-prop-1-en-1-yl-!-4-methyl-tetrahydropyran, more commonly known under the name cis- and trans-rose oxide, which as a rule contains at least 80% of the natural Z-isomers (cis-rose oxide) which are valuable in the perfume industry.

Process for producing a rose oxide

The described compounds of the general formula A, in which the wavy lines mean .alpha. and .beta. configuration and R.sub.1 and R.sub.2 mean hydrogen, methyl or ethyl groups ##STR1## are new and useful as odorants or components or mixtures of odorants or perfume oils. Their production in a method known per se, involves oxidation of isolongifolene obtained from longifolene to isolongifolane, which is then equilibrated with base extraction and/or reduced to isolongifolan-3-ol and this is then reacted with a symmetric acetal of the formula R.sub.2 --OCHR.sub.1 --O--R.sub.2, in which R.sub.1 is hydrogen or methyl and R.sub.2 is methyl, ethyl or propyl.

Isolongifolanol derivatives, their production and their use

The cyclic Isolongifolanone ketals of the general formula A wherein the wavy lines mean .alpha.- and .beta.-configuration and R,R' mean radicals of hydrogen, methyl or ethyl, are new. With preference they are used either as odorants or as components of perfume compositions. They are manufactured from Isolongifolene which is itself produced from Longifolene as is well known. Isolongifolene is oxydized to Isolongifolene-3-on and this is reacted with aliphatic 1,2-diols in apolar solvents with the separation of water.

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Einbeck, Germany

Dietmar Schatkowski