Eppendorf Ag

Dietmar Sander

Lutz Timmann

Andreas Graff

Roger Blum

Rüdiger Huhn

R&uuml;diger Huhn

A piezoelectrically controllable microfluid actor system, comprising a planar substrate which has at least one cavity on at least one side and has at least one passage which has an aperture in the cavity, and at least one diaphragm which has its border mounted on one side of the substrate so as to span the cavity, which has at least two superposed and interconnected diaphragm layers of which at least one is an electrically controllable piezoceramic element, and which is adapted to be deflected into the cavity by means of an electric drive.

Piezoelectrically controllable microfluid actor system

Method for dosing liquid volumes, wherein a sample pickup portion with a pickup volume, the boundary of which is perforated with a liquid passage guiding to the outside and a gas passage, is dipped into a liquid with the liquid passage, a negative pressure is suddenly applied to the gas passage, which is generated by a gas displacement system, a drive of the gas displacement system is readjusted such that a constant negative working pressure exists in the sample pickup portion, the taken sample volume is detected with the aid of the readjusted driving path of the drive, the detected taken volume is compared with a predetermined value of the volume that is to be taken, when the predetermined value is reached by the taken volume, the negative pressure applied on the sample pickup portion is suddenly abated, the sample pickup portion with the liquid passage is pulled out of the liquid the sample pickup portion with the liquid passage is directed towards a releasing location, one ore more flow parameters is/are determined from the values of the taken volume, the negative working pressure and the time period required to take up the volume, an overpressure is applied to the gas passage of the sample pickup portion, the moment at which a volume that is to be released is released is determined with the aid of the flow parameter(s) and the overpressure, and when the moment is reached, the overpressure applied to the sample pickup portion is suddenly abated.

Method of dosing liquid volumes and apparatus for the execution of the method

A microfluidic accumulating and proportioning component, including:

Microfluidic accumulating and proportioning component

A system for detecting fluids in a microfluidic component having at least one microchannel including a limitation wall which has two surfaces which, facing the microchannel in a transparent area, are inclined towards each other at an acute angle, with the system further including a photo transmitter and a photo receiver which are disposed outside the component and are directed to the inclined surfaces in the transparent area of the limitation wall in such a way that if a gas is waiting in the microchannel on the two surfaces, a light ray emitted by the photo transmitter impinges on the photo receiver following a total reflection on the two surfaces and, if a liquid is waiting in the microchannel, the light ray enters the microchannel on at least one of the two surfaces and, as a result, the incidence of light into the photo receiver is reduced or prohibited.

System for detecting fluids in a microfluidic component

A gas cushion proportioning microsystem to proportion liquid volumes in the microliter and sub-microliter ranges, comprising a liquid reservoir including a storage space for the liquid being proportioned the boundary line of which is broken through by an outwardly leading liquid passage and a gas passage, a gas displacement system which has a micropump to pump a gas and a connection to the gas passage, and a proportioning control in an operative communication with the micropump to generate a negative pressure or positive pressure by actuating the micropump and to apply the negative pressure or positive pressure to the liquid reservoir in order to receive liquid in the storage space through the liquid passage or to deliver it from said space.

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Hamburg, Germany

Dietmar Sander