Sanofi

Sanofi-a Ventis Deutschland Gmbh

Dietmar Hammen

Thomas Klemm

Michael Schabbach

Christoph Dette

Alexander Allerdings

Christian Pommereau

Paul Edward Jansen

Ulrich Brueggemann

Bernd Kuehn

Martin Otten

Iwo Ilnicki

A drug injection device comprising: a cartridge configured to hold a volume of a drug; one or more processors configured to operate in at least an enabled state and a sleep state, wherein the one or more processors are configured to control an operation of the drug injection device while the one or more processors are in the enabled state; a member disposed in the cartridge, the member including at least two conductive surfaces electrically connected to the one or more processors; and a drive mechanism including a conductive element spaced from the at least two conductive surfaces, wherein the one or more processors are configured to enter the enabled state from the sleep state when the conductive element makes electrical contact with the at least two conductive surfaces.

Conserving power in an injection device

Implementations of the present disclosure are directed to an injection device that includes a medicament reservoir, a stopper including a rigid core and an ultrasound probe disposed in a housing, the ultrasound probe configured to transmit an emitted ultrasound signal through the rigid core along a longitudinal direction of the rigid core into the medicament reservoir and to receive an ultrasound signal generated by reflections of the emitted ultrasound signal, the reflections including at least a reflection from a distal end of the medicament reservoir, a control component configured to be electronically coupled with the ultrasound probe and to process the ultrasound signal to generate injection device data, and an antenna configured to be electronically coupled with the control component and to transmit the injection device data to an external computing device.

Integration of an ultrasound sensor in a plunger stopper of an injection device

Implementations of the present disclosure are directed to a module for attachment to an injection device that includes a flexible carrier foil configured to be attached to a surface of the injection device independent of a geometry of the surface, at least one light emitting diode attached to the flexible carrier foil in a first position and configured to emit a light signal in a direction based on the first position through a transparent wall of the injection device, at least one photodiode attached to the flexible carrier foil in a second position relative to the first position, the at least one photodiode being configured to detect at least a portion of the light signal from a direction based on the second position and being configured to emit an electrical signal based on the light signal to a microprocessor, and wherein the microprocessor is configured to receive the electrical signal emitted by the photodiode and to determine the position of a stopper and the amount of the fluid within the injection device based at least in part on the electrical signal.

Flexible modules for injection devices

The present disclosure relates to a medicament delivery device comprising at least one microneedle for delivering a medicament to a patient, and a system configured to enhance the penetration of the medicament into skin of the patient.

Medicament delivery device

The present disclosure relates to a medicament delivery device comprising a medicament receiving element, at least one fluid chamber having a fluid outlet configured to direct fluid vapour towards the medicament receiving element, a heating element for heating the fluid in the at least one fluid chamber. The device is configured such that, in use, the heating element heats the fluid in the at least one fluid chamber to at least partially evaporate the fluid so that the vapor pressure in the at least one fluid chamber increases until the fluid is expelled out of the at least one fluid chamber through the fluid outlet towards the medicament receiving element and entrains the medicament towards the patient's skin.

A stopper is disclosed herein. The stopper is configured to be disposed within a medical cartridge. The stopper includes a shell defining a cavity, a core arranged within the cavity, and at least one electronic device embedded within the core, wherein the at least one electronic device includes a sensor and wherein the shell is configured to pass a sensing signal therethrough.

Cartridge with distributed electronic components

Implementations of the present disclosure are directed to an injection device () that includes a medicament reservoir (), a stopper () including a rigid core () and an ultrasound probe () disposed in a housing, the ultrasound probe configured to transmit an emitted ultrasound signal through the rigid core along a longitudinal direction of the rigid core into the medicament reservoir and to receive an ultrasound signal generated by reflections of the emitted ultrasound signal, the reflections including at least a reflection from a distal end of the medicament reservoir, a control component () configured to be electronically coupled with the ultrasound probe and to process the ultrasound signal to generate injection device data, and an antenna () configured to be electronically coupled with the control component and to transmit the injection device data to an external computing device ().

An injection device is provided, comprising a cartridge configured to hold a volume of fluid, the cartridge having a proximal end and a distal end through which the fluid is dispensed; a first stopper disposed in the cartridge and configured to move from the proximal end toward the distal end to cause the fluid to be dispensed through the distal end of the cartridge; a second stopper disposed at the distal end of the cartridge, the second stopper including an aperture through which the fluid is dispensed; a reflector disposed at the distal end of the cartridge; and a transmitter and a receiver disposed in the first stopper, the transmitter configured to transmit one or more waves toward the reflector and the receiver configured to receive reflections of the one or more waves from at least the reflector.

Cartridge for dosage sensing

A medicament delivery device comprises a delivery assembly for transdermally delivering medicament to a patient and a system for providing information on the volume of medicament in the device. The system comprises a sensing unit configured to measure at least one physical parameter dependent on the volume of medicament in the device.

A method of performing character isolation in an optical character recognition process, the method comprising receiving image data representing one or more character columns, determining a number of black pixels in each column of the image data, defining a vertical separation threshold which is a maximum number of black pixels in a column, dividing the columns into different pixel groups and groups of excluded columns by excluding any columns with a number of black pixels below the vertical separation threshold, identifying the pixel group representing the left most character column in the image data, determining whether there are one or two pixel groups representing character columns in the image data and, if it is determined that there are two pixel groups representing character columns, using a predetermined width value for a right most character column in order to identify a right hand boundary of the right most character column.

Device and method for performing optical character recognition

A method of recording a medicament dose using a data collection device comprises capturing an image of a medicament dose indicator of a medicament delivery device, adjusting a scale of said image, adjusting said image for skew of one or more characters displayed by the medicament dose indicator, determining the position of at least one of said one or more characters in the image, identifying the at least one character using optical character recognition and determining a medicament dose indicator by the medicament dose indicator based on a result of the optical character recognition. The method may be performed using a handheld electronic device comprising a camera, such as a cellphone, a tablet computer or other device. A computer program for controlling a data collection device to perform the method may be provided in the form of a software application or 'app'.

Growing community of inventors

Frankfurt am Main, Germany

Dietmar Hammen