Uniwersytet Lodzki

Basf Se Corporation

Leibniz-institut Fuer Polymerforschung Dresden E.v.

Dietmar Appelhans

Ida Franiak-Pietryga

Maria Bryszewska

Barbara Klajnert-Maculewicz

Bernd Bruchmann

Monika Haberecht

Holger Türk

Dieter Lehmann

Daniel Schönfelder

Michaela Gedan-Smolka

Victor Boyko

The subject matter of the invention relates to the method of administering the polypropyleneimine dendrimer of the fourth generation, coated with maltotriose, of a general formula I, wherein 25 to 45% of R substituents stand for a maltotriose residue and each of the remaining R substituents is H, to a human subject. The dendrimer of the formula I is designated in short as PPI-G4-OS-Mal-III, where PPI-G4 stands for the 4th generation of polypropyleneimine dendrimer, OS (Open Shell)&#x2014;for open coat, Mal-III for maltotriose (trisaccharide made of 3 &#x3b1;-glucose residues).

Application of maltotriose-coated 4th generation poly(propyleneimine) dendrimer PPI-G4-OS-Mal-III

The application of maltotriose-coated 4th generation polypropyleneimine dendrimer PPI-G4-OS-Mal-III containing 25-45% of peripheral amines groups coated with maltotriose particles to make a drug for treating neoplastic proliferation diseases, particularly chronic lymphocytic leukemia.

Application of maltotriose-coated 4th generation polypropyleneimine dendrimer PPI-G4-OS-MAL-III

A process for solubilizing hydrophobic active ingredients in aqueous medium, which comprises using, as an assistant, at least one hyperbranched polymer (A) which is obtainable by reacting at least one hyperbranched polymeric compound having at least one primary or secondary amino group per molecule (a), selected from

Process for solubilizing hydrophobic active ingredients in aqueous medium

The invention is used in the field of chemistry and relates to coatings which can be used, for example, for the production of paint films, and a method for production thereof. The object of the invention is to describe permanent coatings with hydrophobic to ultrahydrophobic properties. The object is attained by hydrophobic permanent coatings of a crosslinked layer of a hardener component (A) and resin component (B), whereby (A) and/or (B) comprise chemically coupled lateral and/or terminal perfluoroalkyl groups with at least one trifluoromethyl end group, with a coupling between the layer and the surface region of the substrate. The object is further attained with a method in which the coating agent containing perfluoroalkyl groups is applied to a surface in the form of a melt, powder, dispersion or solution, with input of energy a film formation is carried out in one or more stages with or without a partial cross-linking and at least one partial coupling and subsequently again with input of energy a complete cross-linking of the layer is carried out.

Hydrophobic permanent coatings on substrates and methods for production thereof

Growing community of inventors

Dresden, Germany

Dietmar Appelhans