Sanofi-a Ventis Deutschland Gmbh

Sanofi-aventis

Sanofi

Dieter Schmoll

Elisabeth Defossa

Dieter Kadereit

Andreas W Herling

Thomas Klabunde

Sven Ruf

Karl-Ulrich Wendt

Stefanie Keil

Johanna Kuhlmann-Gottke

Karl-Christian Engel

Gerhard Zoller

Karl Schoenafinger

Guido Haschke

Ingo Focken

Axel Dietrich

Marco Mueller

Axel Deitrich

Marco MÜLLER

Johanna Kuhlmann

Heterocyclic derivatives, processes for their preparation, medicaments comprising these compounds, and the use thereof. The invention relates to compounds of the formula I in which the radicals R1, R2, R3, R4, W, A, B, D, E, G, L, M, R, T and Y have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example for the treatment of the metabolic syndrome, insulin resistance, obesity and diabetes. 

Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof

The present invention relates to substituted phenothiazines with a double bond and physiologically acceptable salts thereof, and their use as a medicament.

Phenothiazine derivative having a double bond, method for the production thereof, and use thereof as a pharmaceutical

The invention relates to compounds of the formula I, wherein R1, R2, R3, R4, R5, R6, R7, A and B are as defined herein, the pharmaceutical compositions and the uses as pharmaceuticals.

Phenothiazin derivatives, method for the production thereof and use thereof as pharmaceuticals

The invention relates to heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.

Heterocyclically substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments

The invention relates to cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.

Cycloalkyl-substituted 7-amino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments

7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments The invention relates to 7-phenylamino-4-quinolone-3-carboxylic acid derivatives and to the physiologically tolerated salts and physiologically functional derivatives thereof. The invention relates to compounds of the formula I in which the radicals have the stated meanings, and to the physiologically tolerated salts thereof. The compounds are suitable for example as medicaments for the prevention and treatment of type 2 diabetes.

7-Phenylamino-4-quinolone-3-carboxylic acid derivatives, process for their preparation and their use as medicaments

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Frankfurt-am-Main, Germany

Dieter Schmoll