Sartorius Stedim Biotech Gmbh

Elcomax Membranes Gmbh

Volkswagen Ag

Lanxess Deutschland Gmbh

Rhein Chemie Rheinau Gmbh

Carl Freudenberg Kg

Dieter Melzner

Annette Reiche

Suzana Kiel

Denise Van Rossum

Oliver Gronwald

Werner Obrecht

Stefan Weisshaar

Ulrich Maehr

Susanne Drebing

Ulrich Mahr

Stefan Haufe

Hans-Heinrich Hörl

Thomas Früh

Louis Villain

Torsten Ziser

Domnik Bayer

Thomas Scheper

Johanna-Gabriela Walter

Manfred Gottlöber

Thomas Schueler

Gabriel Nino-Amézquita

Frank Stahl

Carsten Zeilinger

Alfons Kesting

Franziska Bäthe

Ulrich Mähr

Eric Jallérat

Sandra Van Der Kruijs

Gabriel NIÑO-AMÉZQUITA

Thomas FRÜH

Carsten Pretorius

The present invention relates to a multiparameter lateral flow strip (), comprising a microporous membrane layer () supported on a liquid-impermeable support layer (), for lateral flow of a liquid through the microporous membrane layer (), wherein the microporous membrane layer () has two or more flow lanes () in the direction of lateral flow, wherein said two or more flow lanes () are separated by hydrophobic separation channels (), and wherein each of said two or more flow lanes () comprises a detection spot () including a binding agent, wherein said two or more flow lanes () are isomorphic lanes. Furthermore, the present invention relates to a multiparameter lateral flow immunoassay device comprising said multiparameter lateral flow membrane (), the use of said multiparameter configured lateral flow membrane () in an immunological test, as well as to a method for the manufacture of said multiparameter configured lateral flow membrane ().

Lateral flow membrane designed for multiparameter readouts and compact multiparameter lateral flow immunoassay device comprising the same

The present invention relates to a patterned membrane structure comprising a microporous membrane layer, wherein the microporous membrane layer includes a plurality of flow lanes, the flow lanes are separated by hydrophobic separation channels, and the flow lanes and hydrophobic separation channels form a repetitive pattern; and a method for manufacture of the patterned membrane structure. The patterned membrane structure according to the present invention represents an industrial scale precursor of membranes such as a multiparameter lateral flow membrane comprising separated flow lanes.

Patterned membrane structure

The present invention relates to a crosslinked unreinforced cellulose hydrate membrane crosslinked using at least two different crosslinking agents, to a method for the production thereof and to the use of the crosslinked unreinforced cellulose hydrate membrane according to the invention.

Crosslinked unreinforced cellulose hydrate membrane, method for the production thereof, and use thereof

The present invention relates to a lateral flow membrane arrangement (), comprising a microporous membrane layer () and a liquid-impermeable support layer (), for lateral flow of a liquid through the microporous membrane layer (), wherein the microporous membrane layer () is supported on the liquid-impermeable support layer () and has at least one detection zone () and at least one non-detection zone, wherein binding agents are immobilized in the at least one detection zone (), the liquid-impermeable support layer () has at least one zone having a large thickness and at least one zone having a small thickness, the microporous membrane layer () is supported on the liquid-impermeable support layer () such that said at least one detection zone is provided above said at least one zone of the support layer having a large thickness and said at least one non-detection zone is provided above said at least one zone of the support layer having a small thickness, the zones are oriented in a direction orthogonally to the lateral flow direction (a) of said liquid, the detection zone () has a thickness () of 100 to 150 &#x3bc;m over the entire width of the membrane, the non-detection zone has a thickness () of at most 300 &#x3bc;m over the entire width of the membrane, and the lateral flow membrane arrangement () has a constant thickness (), as well as to a lateral flow immunoassay device comprising said membrane arrangement ().

Lateral flow membrane arrangement and lateral flow immunoassay device comprising the same

The present invention relates to a microarray device for the screening or the finding of protein inhibitors, to a method for the production thereof, and to a corresponding method for screening or finding protein inhibitors. The microarray device according to the invention comprises a solid supporting element having a support material, at least one protein immobilized thereon for which inhibitors are to be screened or found, and at least one known inhibitor of the at least one protein, the inhibitor being bound to the at least one protein and comprising a detectable label.

Microarray device for screening or locating HSP90 inhibitors or inhibitors of further disease-relevant target structures

The present invention relates to a polymer electrolyte membrane for fuel cells, comprising a polymer matrix of at least one basic polymer and one or more doping agents, wherein particles containing ionogenic groups and having a mean particle diameter in the nanometer range are embedded in the polymer matrix and the particles containing ionogenic groups are distributed homogeneously in the polymer matrix in a concentration of less than 50% relative to the weight of the polymer matrix, as well as to the production and use of same, especially in high-temperature fuel cells.

Polymer electrolyte membrane with functionalized nanoparticles

The invention relates to hybrid membranes that are composed of an organic polymer and an inorganic polymer, a method for producing hybrid membranes, and the use of said hybrid membranes in polymer electrolyte membrane fuel cells. The inventive hybrid membranes comprise at least one alkaline organic polymer and at least one inorganic polymer. Said polymers are blended together at a molecular level. The inorganic polymer is formed from at least one precursor monomer when the membrane is produced. The disclosed membranes are characterized in that the same are provided with high absorptivity for doping agents, have a high degree of mechanical and thermal stability in both an undoped and doped state, and feature permanently high proton conductivity.

Hybrid membranes, method for production of hybrid membranes and fuel cells using such hybrid membranes

A membrane-electrode assembly and polymer electrolyte fuel cells and methods of production thereof, in which a polymer membrane, containing at least one basic polymer membrane, is sandwiched between two flat gas diffusion electrodes each of which is loaded with a dopant, whereby after reaching a mass transport equilibrium for the exchange of the dopant between the gas diffusion electrodes and the polymer membrane, the polymer membrane has a conductivity of at least 0.1 S/m at a temperature of no less than 25&#xb0; C.

Membrane-electrode assembly, polymer membranes for a membrane-electrode assembly, polymer electrolyte fuel cells, and methods for the production thereof

A membrane for fuel cells, which is characterized by a homogeneous absorption and good retention of doping agents, and which guarantees a high mechanical stability at high temperatures when doped. Such membranes consist of at least one polymer, whose nitrogen atoms are chemically bonded to a central atom of a derivative of a polybasic inorganic oxo acid. The membranes are produced from polymer solutions that are devoid of water and oxo acid derivatives, by heating the solution that has been introduced into a membrane mold until a self-supporting membrane has been formed and then by thermally regulating the latter. Inventive fuel cells having a membrane electrode assembly (MEA) that comprises a membrane of the invention and phosphoric acid as the doping agent have, for example, an impedance of 0.5-1 &#x3a9;cmat a measuring frequency of 1000 Hz and at an operating temperature of 160&#xb0; C. and a gas flow for hydrogen of 170 mL/min and for air of 570 mL/min. They can be used as high-temperature polyelectrolyte membrane fuel cells for a working temperature of up to at least 250&#xb0; C.

Membranes for fuel cells, method for producing said membranes and production of fuel cells using membranes of this type

A proton-conducting electrolyte membrane is disclosed, comprising at least one base material and at least one dopant, which is the reaction product of an at least dibasic inorganic acid with an organic compound, comprising one acidic hydroxyl group, or the condensation product of said compound with a polybasic acid. The membrane may be produced by a single step method, which avoids the use of dangerous materials and environmental pollutants. Subsequent doping of the membrane, e.g., in conjunction with assembly of the membrane electrode assembly (MEA) is not excluded. The electrolyte membrane has a high and constant mechanical stability and flexibility, excellent chemical and thermal stability and a high and constant conductivity. The membrane may be used in a fuel cell in a wide temperature range from 50&#xb0; C. to more than 200&#xb0; C., for example, whereby the fuel cell has a high and constant power level over the entire temperature range.

Proton-conducting electrolyte membrane method for production and use thereof in a fuel cell

A membrane electrode assembly (MEA) for a fuel cell, which has a planar polymer membrane. This membrane, in a tangentially inner area, is coated on both sides with electrode structure, and, in a tangentially outer area projecting at least on one side beyond the electrode structure coating, is connected to a sealing member. A marginal zone of the polymer membrane is embedded in the elastomer sealing member. The sealing member extends tangentially inward to a transition area that lies tangentially between the outer area and the inner area, where it overlaps the electrode structures on outer faces of the electrode structures, on both of the sides of the polymer membrane.

Membrane electrode assembly for a fuel cell

Growing community of inventors

Göttingen, Germany

Dieter Melzner