Ciba-geigy Corporation

Dieter Beck

Karl Schenker

Angelo Storni

Raymond Bernasconi

Max Wilhelm

Alberto Rossi

9-(2-A-3-R-propyl)-9,10-dihydro-9,10-ethano-anthracenes containing the nucleus of the formula ##STR1## wherein R denotes a secondary or tertiary amino group and A denotes a free, etherified or acylated hydroxyl group, their pharmaceutically acceptable salts are useful as psychotropics, especially as anti-depressants.

Pharmaceutical preparation using

9-(2-A-3-R-propyl)-9,10-dihydro-9,10-ethanoanthracenes containing the nucleus of the formula ##STR1## wherein R denotes a secondary or tertiary amino group and A denotes a free, etherified or acylated hydroxyl group, their pharmaceutically acceptable salts are useful as psychotropics, especially as anti-depressants.

9-(2-Hydroxy-3-amino-propyl)-9,10-dihydro-9,10-ethano-anthracenes and

Compounds of the formula ##EQU1## in which Ph represents an ortho-phenylene radical which contains in position 4 or 5 an unsubstituted or substituted hydrocarbon radical of aliphatic character, R represents a lower alkyl radical or especially a hydrogen atom, Z represents a free, esterified or amidated carboxyl group, A represents an ethylene radical and X stands for two hydrogen atoms or especially for an oxo group, are useful as chemotherapeutic and prophylactic agents against pain and inflammation.

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Basel, Switzerland

Dieter Beck