Beecham Group Plc

Beecham-wuelfing Gmbh & Co. Kg

Dieter Angersbach

Charles D Nicholson

Geoffrey Stemp

John M Evans

Joachim E Goring

Brian Morgan

Jonathan R Arch

Compounds of the formula ##STR1## as defined in the specification, and processes for their preparation and methods of using the compounds for the treatment of hypertension in mammals, such as humans and for the treatment and/or prophylaxis of cerebrovascular disorders and/or disorders associated with cerebral senility in mammals, such as humans.

Di/tetra-hydroquinolines

A method for the treatment of cerebral vascular and neuronal degenerative disorders associated with learning, memory and cognitive dysfunctions including cerebral senility, multi-infarct dementia and senile dementia of the Alzheimer type and/or peripheral vascular disease and/or proliferative skin disease in mammals, such as humans, which comprises administering to the mammal in need of such treatment an effective amount of 1,3-di-n-butyl-7-(2-oxypropyl) xanthine or a pharmaceutically acceptable salt thereof.

Novel treatment

Growing community of inventors

Gronau, Germany

Dieter Angersbach